TY  - JOUR
AU  - Pais, Patricia
AU  - Yun, Seong Dae
AU  - Shah, N. Jon
TI  - Pre-processing of Sub-millimeter GE-BOLD fMRI Data for Laminar Applications
JO  - Frontiers in neuroimaging
VL  - 1
SN  - 2813-1193
CY  - Lausanne
PB  - Frontiers Media SA
M1  - FZJ-2022-02079
SP  - 869454
PY  - 2022
AB  - Over the past 30 years, brain function has primarily been evaluated non-invasively using functional magnetic resonance imaging (fMRI) with gradient-echo (GE) sequences to measure blood-oxygen-level-dependent (BOLD) signals. Despite the multiple advantages of GE sequences, e.g., higher signal-to-noise ratio, faster acquisitions, etc., their relatively inferior spatial localization compromises the routine use of GE-BOLD in laminar applications. Here, in an attempt to rescue the benefits of GE sequences, we evaluated the effect of existing pre-processing methods on the spatial localization of signals obtained with EPIK, a GE sequence that affords voxel volumes of 0.25 mm3 with near whole-brain coverage. The methods assessed here apply to both task and resting-state fMRI data assuming the availability of reconstructed magnitude and phase images.
LB  - PUB:(DE-HGF)16
C6  - 37555171
UR  - <Go to ISI:>//WOS:001537169300001
DO  - DOI:10.3389/fnimg.2022.869454
UR  - https://juser.fz-juelich.de/record/907552
ER  -