TY  - THES
AU  - Hardy, Aël
TI  - Role of secondary metabolites in antiphage defense in Streptomyces
VL  - 254
PB  - HHU Duesseldorf
VL  - Dissertation
CY  - Jülich
M1  - FZJ-2022-02080
SN  - 978-3-95806-633-5
T2  - Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies
SP  - 208
PY  - 2022
N1  - Biotechnologie 1
N1  - Dissertation, HHU Duesseldorf, 2022
AB  - Bacteriophages (phages) are viruses preying on bacteria and as such pose a major and ubiquitousthreat to bacterial communities. To cope with viral challenges, bacteria have evolved a diversifiedarsenal of defense systems. However, this repertoire is known to rely predominantly on protein orRNA effectors. On the other hand, bacteria produce an extraordinary diversity of secondarymetabolites, whose physiological function is often unknown. In this thesis, we explore the role ofbacterial secondary metabolites in the defense against phage predation. To this end, we used as amodel system Streptomyces, a prolific producer of secondary metabolites
LB  - PUB:(DE-HGF)3 ; PUB:(DE-HGF)11
UR  - https://juser.fz-juelich.de/record/907554
ER  -