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@PHDTHESIS{Hardy:907554,
      author       = {Hardy, Aël},
      title        = {{R}ole of secondary metabolites in antiphage defense in
                      {S}treptomyces},
      volume       = {254},
      school       = {HHU Duesseldorf},
      type         = {Dissertation},
      address      = {Jülich},
      publisher    = {Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag},
      reportid     = {FZJ-2022-02080},
      isbn         = {978-3-95806-633-5},
      series       = {Schriften des Forschungszentrums Jülich Reihe
                      Schlüsseltechnologien / Key Technologies},
      pages        = {208},
      year         = {2022},
      note         = {Biotechnologie 1; Dissertation, HHU Duesseldorf, 2022},
      abstract     = {Bacteriophages (phages) are viruses preying on bacteria and
                      as such pose a major and ubiquitousthreat to bacterial
                      communities. To cope with viral challenges, bacteria have
                      evolved a diversifiedarsenal of defense systems. However,
                      this repertoire is known to rely predominantly on protein
                      orRNA effectors. On the other hand, bacteria produce an
                      extraordinary diversity of secondarymetabolites, whose
                      physiological function is often unknown. In this thesis, we
                      explore the role ofbacterial secondary metabolites in the
                      defense against phage predation. To this end, we used as
                      amodel system Streptomyces, a prolific producer of secondary
                      metabolites},
      cin          = {IBG-1},
      cid          = {I:(DE-Juel1)IBG-1-20101118},
      pnm          = {2171 - Biological and environmental resources for
                      sustainable use (POF4-217)},
      pid          = {G:(DE-HGF)POF4-2171},
      typ          = {PUB:(DE-HGF)3 / PUB:(DE-HGF)11},
      urn          = {urn:nbn:de:0001-2022083102},
      url          = {https://juser.fz-juelich.de/record/907554},
}