% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Fricke:907814,
      author       = {Fricke, Philipp Moritz and Hartmann, Rudolf and Wirtz,
                      Astrid and Bott, Michael and Polen, Tino},
      title        = {{P}roduction of l-arabinonic acid from l-arabinose by the
                      acetic acid bacterium {G}luconobacter oxydans},
      journal      = {Bioresource technology reports},
      volume       = {17},
      issn         = {2589-014X},
      address      = {Amsterdam},
      publisher    = {Elsevier},
      reportid     = {FZJ-2022-02231},
      pages        = {100965 -},
      year         = {2022},
      note         = {Biotechnologie 1},
      abstract     = {l-Arabinonic acid is a five carbon sugar acid valuable for
                      various potential applications. Based on previous
                      observations that Gluconobacter oxydans 621H oxidizes
                      l-arabinose in the periplasm by the membrane-bound glucose
                      dehydrogenase GdhM yielding l-arabinonic acid, we tested its
                      ability for production. In fed-batch shake flasks without pH
                      control, 17.4 g/L l-arabinonic acid and 5.7 g/L
                      l-arabino-1,4-lactone were obtained. A large fraction of
                      l-arabinose remained unused since acidification of the
                      medium prevented further substrate oxidation. In pH
                      6-controlled fed-batch bioreactors, up to 120 g/L
                      l-arabinonic acid and 13 g/L l-arabino-1,4-lactone could be
                      obtained with strain 621H (144 h). Constitutive
                      overexpression of gdhM did not increase product titers and
                      resulted in reduced biomass formation, yet the gdhM
                      overexpression strain showed higher biomass-specific
                      production (169 g/L/gcdw) compared to 621H (131 g/L/gcdw).
                      The high combined product titer (133 g/L, 814 mM) makes G.
                      oxydans a very promising host for high-level production of
                      l-arabinonic acid.},
      cin          = {IBG-1},
      ddc          = {570},
      cid          = {I:(DE-Juel1)IBG-1-20101118},
      pnm          = {2172 - Utilization of renewable carbon and energy sources
                      and engineering of ecosystem functions (POF4-217)},
      pid          = {G:(DE-HGF)POF4-2172},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:001206651900021},
      doi          = {10.1016/j.biteb.2022.100965},
      url          = {https://juser.fz-juelich.de/record/907814},
}