%0 Journal Article
%A Winter, Johanna
%A Dimroth, Anton
%A Roetzer, Sebastian
%A Zhang, Yunzhe
%A Krämer, Karl-Ludwig
%A Petrich, Christian
%A Matejcek, Christoph
%A Aulenbacher, Kurt
%A Zimmermann, Markus
%A Combs, Stephanie E.
%A Galek, Marek
%A Natour, Ghaleb
%A Butzek, Michael
%A Wilkens, Jan J.
%A Bartzsch, Stefan
%T Heat management of a compact x‐ray source for microbeam radiotherapy and FLASH treatments
%J Medical physics
%V 49
%N 5
%@ 0094-2405
%C College Park, Md.
%I AAPM
%M FZJ-2022-02275
%P 3375 - 3388
%D 2022
%X Background:Microbeam and x-ray FLASH radiation therapy are innovativeconcepts that promise reduced normal tissue toxicity in radiation oncology withoutcompromising tumor control. However, currently only large third-generationsynchrotrons deliver acceptable x-ray beam qualities and there is a need forcompact, hospital-based radiation sources to facilitate clinical translation ofthese novel treatment strategies.Purpose: We are currently setting up the first prototype of a line-focus x-raytube (LFxT), a promising technology that may deliver ultra-high dose rates(UHDRs) of more than 100 Gy/s from a table-top source. The operation of thesource in the heat capacity limit allows very high dose rates with micrometersizedfocal spot widths.Here,we investigate concepts of effective heat managementfor the LFxT, a prerequisite for the performance of the source.Methods: For different focal spot widths, we investigated the temperatureincrease numerically with Monte Carlo simulations and finite element analysis(FEA).We benchmarked the temperature and thermal stresses at the focal spotagainst a commercial x-ray tube with similar power characteristics.We assessedthermal loads at the vacuum chamber housing caused by scattering electrons inMonte Carlo simulations and FEA. Further,we discuss active cooling strategiesand present a design of the rotating target.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:35315089
%U <Go to ISI:>//WOS:000778971300001
%R 10.1002/mp.15611
%U https://juser.fz-juelich.de/record/907897