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@ARTICLE{Maiworm:907955,
      author       = {Maiworm, Anneke and Langner, Robert and Wilm, Stefan and
                      Hermann, Dirk M. and Frohnhofen, Helmut and Gronewold,
                      Janine},
      title        = {{D}eveloping a novel tool to assess the ability to
                      self‑administer medication in non‑demented in‑hospital
                      patients: {ABLYMED} study protocol},
      journal      = {BMC geriatrics},
      volume       = {22},
      number       = {1},
      issn         = {1471-2318},
      address      = {London},
      publisher    = {BioMed Central},
      reportid     = {FZJ-2022-02297},
      pages        = {466},
      year         = {2022},
      abstract     = {Background: Older people often suffer from multimorbidity
                      resulting in polypharmacy. The correct administration of
                      medication is a crucial factor influencing treatment
                      efficacy. However, tools for evaluating the ability to
                      self-administer different dosage forms of medications are
                      lacking. The objectives of the ABLYMED study are to 1)
                      assess the ability to self-administer different dosage forms
                      of medication in older non-demented in-hospital patients who
                      report autonomous management of medication, 2) identify
                      factors influencing the ability to self-administer
                      medication, and 3) develop a standardized tool to validly
                      assess the ability to self-administer different dosage forms
                      of medications based on the final study results. Methods:
                      One hundred in-patients from the department of orthopedics
                      and trauma surgery of the University Hospital Düsseldorf 
                      ≥ 70 years of age and regularly taking ≥ 5 different
                      drugs autonomously will be prospectively recruited into the
                      observational cross-sectional single-center ABLYMED study.
                      Patients undergo an interview addressing demographic and
                      clinical information, medication history (which medications
                      are taken since when, in which dose and dosage form, and
                      subjective proficiency of taking these medications),
                      medication adherence, and factors possibly influencing
                      adherence including personality traits and perceived quality
                      of the medication regimen. Quality of the medication regimen
                      is also rated by clinicians according to validated lists.
                      Further, patients receive a comprehensive geriatric
                      assessment including measures of cognition, mobility, and
                      functional status. The ability to self-administer medication
                      is assessed by having patients perform different tasks
                      related to medication self-administration, which are video
                      recorded and rated by different experts. The patients’
                      self-reported ability will be correlated with the observed
                      performance in the self-administration tasks. Further,
                      factors correlating with the reported and observed ability
                      to self-administer medication will be evaluated using
                      correlation and regression models. Based on the final study
                      results, a novel tool to assess the ability of older
                      patients to self-administer medication will be developed.
                      Discussion: In addition to guideline-based pharmacotherapy,
                      correct intake of prescribed medication is crucial for
                      optimal therapy of multimorbidity in older people. Tools to
                      validly assess the ability of older patients to
                      self-administer different dosage forms of medications are
                      lacking, but should be included in comprehensive geriatric
                      assessments to secure functional health.},
      cin          = {INM-7},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5252 - Brain Dysfunction and Plasticity (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5252},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {35641903},
      UT           = {WOS:000803887500004},
      doi          = {10.1186/s12877-022-03147-8},
      url          = {https://juser.fz-juelich.de/record/907955},
}