000908203 001__ 908203
000908203 005__ 20220621190117.0
000908203 0247_ $$2doi$$a10.1109/NSSMIC.2018.8824424
000908203 037__ $$aFZJ-2022-02454
000908203 1001_ $$0P:(DE-Juel1)168272$$aXu, Hancong$$b0
000908203 1112_ $$a2018 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)$$cSydney$$d2018-11-10 - 2018-11-17$$wAustralia
000908203 245__ $$aResolution Modelling in Projection Space using Factorized Multi-block Detector Response Function
000908203 260__ $$c2018
000908203 3367_ $$0PUB:(DE-HGF)1$$2PUB:(DE-HGF)$$aAbstract$$babstract$$mabstract$$s1655804568_16933
000908203 3367_ $$033$$2EndNote$$aConference Paper
000908203 3367_ $$2BibTeX$$aINPROCEEDINGS
000908203 3367_ $$2DRIVER$$aconferenceObject
000908203 3367_ $$2DataCite$$aOutput Types/Conference Abstract
000908203 3367_ $$2ORCID$$aOTHER
000908203 520__ $$aAbstract:Position emission tomography (PET) images usually suffer from low spatial resolution and signal-to-noise (SNR) ratio. The degradation of image resolution in PET is caused by detection process, e.g. inter-crystal scattering, crystal penetration. An Accurate Detector Response Functions (DRF) allows to model these phenomena and increase the spatial resolution as well as SNR in the iterative image reconstruction. However, fully 3D DRF for pixelated crystal arrays (block) which also considers inter-block penetration and inter-crystal scattering between different blocks still remains challenging. Here we demonstrate the development of an accurate DRF for the Siemens Hybrid MR-BrainPET system with a 9-block model using GATE simulations. Different incident γ rays are described by four parameters (x, y, θ, φ) in Block Coordinate System. Their detection response, comprising a list of fired crystals' id and corresponding detection probability, are stored as an entry of a 4D Look-up Table (LUT) addressed by (x, y, θ, φ). Based on the DRF LUT, a PSF blurring kernel in 4D projection space can be obtained by combining two multi-block DRF according to the intersected block pair for each Line-of-Response. PSF modelling in projection space is implemented in the reconstruction toolkit PRESTO based on the developed DRF LUT. A resolution phantom with 6 types of hot rods is simulated by GATE and reconstructed by PRESTO with MLEM and MLEM-PSF. Visual results demonstrate that with moderate statistics (2.8×10 8 ), MLEM-PSF could recover small bins (5 mm) at the edge of FOV in a more accurate way compared to MLEM. Furthermore, the images of MLEM-PSF show better noise suppression.
000908203 536__ $$0G:(DE-HGF)POF4-5253$$a5253 - Neuroimaging (POF4-525)$$cPOF4-525$$fPOF IV$$x0
000908203 588__ $$aDataset connected to CrossRef Conference
000908203 7001_ $$0P:(DE-HGF)0$$aScheins, Juergen$$b1
000908203 7001_ $$aCaldeira, Liliana$$b2
000908203 7001_ $$0P:(DE-Juel1)165812$$aLenz, Mirjam$$b3
000908203 7001_ $$0P:(DE-Juel1)169363$$aMa, Bo$$b4
000908203 7001_ $$0P:(DE-Juel1)164254$$aLerche, Christoph$$b5$$ufzj
000908203 7001_ $$0P:(DE-Juel1)131794$$aShah, N. J.$$b6$$ufzj
000908203 773__ $$a10.1109/NSSMIC.2018.8824424
000908203 909CO $$ooai:juser.fz-juelich.de:908203$$pVDB
000908203 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)164254$$aForschungszentrum Jülich$$b5$$kFZJ
000908203 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131794$$aForschungszentrum Jülich$$b6$$kFZJ
000908203 9131_ $$0G:(DE-HGF)POF4-525$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5253$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vDecoding Brain Organization and Dysfunction$$x0
000908203 9201_ $$0I:(DE-Juel1)INM-11-20170113$$kINM-11$$lJara-Institut Quantum Information$$x0
000908203 9201_ $$0I:(DE-Juel1)INM-4-20090406$$kINM-4$$lPhysik der Medizinischen Bildgebung$$x1
000908203 9201_ $$0I:(DE-Juel1)VDB1046$$kJARA-BRAIN$$lJülich-Aachen Research Alliance - Translational Brain Medicine$$x2
000908203 980__ $$aabstract
000908203 980__ $$aVDB
000908203 980__ $$aI:(DE-Juel1)INM-11-20170113
000908203 980__ $$aI:(DE-Juel1)INM-4-20090406
000908203 980__ $$aI:(DE-Juel1)VDB1046
000908203 980__ $$aUNRESTRICTED