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@INPROCEEDINGS{More:908493,
author = {More, Shammi and Antonoupolous, Georgios and Hoffstaedter,
Felix and Caspers, Julian and Eickhoff, Simon and Patil,
Kaustubh},
title = {{B}rain-age prediction: a systematic comparison of machine
learning workflows},
reportid = {FZJ-2022-02636},
year = {2022},
abstract = {Prediction of age using anatomical brain MRI, i.e., brain
age, is proving valuable in exploring accelerated aging
(brain age delta) as a proxy for aging-related diseases and
crucial future health outcomes [1]. While various data
representations and machine learning (ML) algorithms have
been used for brain-age prediction [2,3], the impact of
these choices on prediction accuracy remains
uncharacterized. Moreover, several methodological challenges
remain before a predictive model can be deployed in the real
world; (1) robust within-site performance, (2) accurate
cross-site prediction and, (3) consistent prediction for the
same individual. To fill this gap, we systematically
evaluated 70 workflows consisting of ten feature spaces
derived from grey matter (GM) images and seven ML algorithms
with diverse inductive biases to establish guidelines for
designing brain-age prediction workflows.},
month = {Jun},
date = {2022-06-19},
organization = {Organization for Human Brain Mapping,
Glasgow (Scotland), 19 Jun 2022 - 23
Jun 2022},
subtyp = {After Call},
cin = {INM-7},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525) / 5254 - Neuroscientific Data Analytics and AI
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251 / G:(DE-HGF)POF4-5254},
typ = {PUB:(DE-HGF)24},
url = {https://juser.fz-juelich.de/record/908493},
}