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@ARTICLE{Quabs:908830,
      author       = {Quabs, Julian and Caspers, Svenja and Schöne, Claudia and
                      Mohlberg, Hartmut and Bludau, Sebastian and Dickscheid, Timo
                      and Amunts, Katrin},
      title        = {{C}ytoarchitecture, probability maps and segregation of the
                      human insula},
      journal      = {NeuroImage},
      volume       = {260},
      issn         = {1053-8119},
      address      = {Orlando, Fla.},
      publisher    = {Academic Press},
      reportid     = {FZJ-2022-02866},
      pages        = {119453 -},
      year         = {2022},
      abstract     = {The human insular cortex supports multifunctional
                      integration including interoceptive, sensorimotor, cognitive
                      and social-emotional processing. Different concepts of the
                      underlying microstructure have been proposed over more than
                      a century. However, a 3D map of the cytoarchitectonic
                      segregation of the insula in standard reference space, that
                      could be directly linked to neuroimaging experiments
                      addressing different cognitive tasks, is not yet available.
                      Here we analyzed the middle posterior and dorsal anterior
                      insula with image analysis and a statistical mapping
                      procedure to delineate cytoarchitectonic areas in ten human
                      postmortem brains. 3D-probability maps of seven new areas
                      with granular (Ig3, posterior), agranular (Ia1, posterior)
                      and dysgranular (Id2-Id6, middle to dorsal anterior)
                      cytoarchitecture have been calculated to represent the new
                      areas in stereotaxic space. A hierarchical cluster analysis
                      based on cytoarchitecture resulted in three distinct
                      clusters in the superior posterior, inferior posterior and
                      dorsal anterior insula, providing deeper insights into the
                      structural organization of the insula. The maps are openly
                      available to support future studies addressing relations
                      between structure and function in the human insula.},
      cin          = {INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525) / HBP SGA3 - Human Brain Project Specific Grant
                      Agreement 3 (945539)},
      pid          = {G:(DE-HGF)POF4-5251 / G:(EU-Grant)945539},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {35809885},
      UT           = {WOS:000843953200003},
      doi          = {10.1016/j.neuroimage.2022.119453},
      url          = {https://juser.fz-juelich.de/record/908830},
}