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024 7 _ |a 10.1093/bioadv/vbac053
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024 7 _ |a 2128/31666
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037 _ _ |a FZJ-2022-03031
082 _ _ |a 004
100 1 _ |a Sachs, Christian Carsten
|0 P:(DE-Juel1)157870
|b 0
245 _ _ |a CellSium – versatile cell simulator for microcolony ground truth generation
260 _ _ |a Oxford
|c 2022
|b Oxford University Press
336 7 _ |a article
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336 7 _ |a ARTICLE
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336 7 _ |a Journal Article
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500 _ _ |a Funding: - Deutsche Forschungsgemeinschaft [WI 1705/16-2], [491111487]- the President’s Initiative and Networking Funds of the Helmholtz Association of German Research Centres [SATOMI ZT-I-PF-04-011]- Helmholtz School for Data Science in Life, Earth and Energy (HDS-LEE)
520 _ _ |a To train deep learning based segmentation models, large ground truth data sets are needed. To address this need in microfluidic live-cell imaging, we present CellSium, a flexibly configurable cell simulator built to synthesize realistic image sequences of bacterial microcolonies growing in monolayers. We illustrate that the simulated images are suitable for training neural networks. Synthetic time-lapse videos with and without fluorescence, using programmable cell growth models, and simulation-ready 3D colony geometries for computational fluid dynamics (CFD) are also supported.
536 _ _ |a 2172 - Utilization of renewable carbon and energy sources and engineering of ecosystem functions (POF4-217)
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700 1 _ |a Ruzaeva, Karina
|0 P:(DE-Juel1)180323
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700 1 _ |a Seiffarth, Johannes
|0 P:(DE-Juel1)176923
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700 1 _ |a Wiechert, Wolfgang
|0 P:(DE-Juel1)129076
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700 1 _ |a Berkels, Benjamin
|0 P:(DE-HGF)0
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700 1 _ |a Nöh, Katharina
|0 P:(DE-Juel1)129051
|b 5
|e Corresponding author
773 _ _ |a 10.1093/bioadv/vbac053
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|t Bioinformatics advances
|v 2
|y 2022
|x 2635-0041
856 4 _ |u https://juser.fz-juelich.de/record/909145/files/Invoice_E15493826.pdf
856 4 _ |y OpenAccess
|u https://juser.fz-juelich.de/record/909145/files/vbac053.pdf
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913 1 _ |a DE-HGF
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