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@ARTICLE{Fabender:909505,
author = {Faßbender, Ronja V. and Goedecke, Jana and
Visser-Vandewalle, Veerle and Fink, Gereon R. and Onur,
Oezguer A.},
title = {{S}timulationsverfahren zur {B}ehandlung von {D}emenzen},
journal = {Fortschritte der Neurologie, Psychiatrie},
volume = {90},
number = {07/08},
issn = {0015-8194},
address = {Stuttgart [u.a.]},
publisher = {Thieme},
reportid = {FZJ-2022-03211},
pages = {336 - 342},
year = {2022},
abstract = {Due to the increasing number of cases of Alzheimer’s
disease and the relatively moderate success with the
available symptomatic and causal pharmacological therapies,
there is a considerable need to explore non-pharmacological
treatment options. In the field of non-invasive brain
stimulation (NIBS), various methods have been investigated,
particularly transcranial magnetic stimulation and
transcranial electrical stimulation. In addition, deep brain
stimulation (DBS) is currently being researched as an
innovative method for targeted neuromodulation. Both
non-invasive and invasive approaches aim to modulate
neuronal activity and improve cognitive-mnestic functions.
Secondary mechanisms such as long-term potentiation in NIBS
or neurogenesis in DBS could also achieve long-term positive
effects. Preclinical and clinical studies have already shown
promising results in patients in early stages of
Alzheimer’s disease. However, inconsistent study and
stimulation protocols and small sample sizes make it
difficult to assess efficacy. Further research is warranted
to enable the use of non-invasive or invasive
neuromodulatory approaches in clinical practice in the near
future.},
cin = {INM-3},
ddc = {150},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)16},
pubmed = {35483888},
UT = {WOS:000788274200001},
doi = {10.1055/a-1787-0335},
url = {https://juser.fz-juelich.de/record/909505},
}