TY  - JOUR
AU  - Galldiks, Norbert
AU  - Langen, Karl-Josef
AU  - Albert, Nathalie L
AU  - Law, Ian
AU  - Kim, Michelle M
AU  - Villanueva-Meyer, Javier E
AU  - Soffietti, Riccardo
AU  - Wen, Patrick Y
AU  - Weller, Michael
AU  - Tonn, Joerg C
TI  - Investigational PET tracers in neuro-oncology—What’s on the horizon? A report of the PET/RANO group
JO  - Neuro-Oncology
VL  - 24
IS  - 11
SN  - 1522-8517
CY  - Oxford
PB  - Oxford Univ. Press
M1  - FZJ-2022-03213
SP  - 1815–1826
PY  - 2022
AB  - Many studies in patients with brain tumors evaluating innovative PET tracers have been published in recent years, and the initial results are promising. Here, the Response Assessment in Neuro-Oncology (RANO) PET working group provides an overview of the literature on novel investigational PET tracers for brain tumor patients. Furthermore, newer indications of more established PET tracers for the evaluation of glucose metabolism, amino acid transport, hypoxia, cell proliferation, and others are also discussed. Based on the preliminary findings, these novel investigational PET tracers should be further evaluated considering their promising potential. In particular, novel PET probes for imaging of translocator protein and somatostatin receptor overexpression as well as for immune system reactions appear to be of additional clinical value for tumor delineation and therapy monitoring. Progress in developing these radiotracers may contribute to improving brain tumor diagnostics and advancing clinical translational research.
LB  - PUB:(DE-HGF)16
C6  - 35674736
UR  - <Go to ISI:>//WOS:000807656300001
DO  - DOI:10.1093/neuonc/noac131
UR  - https://juser.fz-juelich.de/record/909507
ER  -