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@INPROCEEDINGS{Linssen:909578,
author = {Linssen, Charl and Korcsak-Gorzo, Agnes and Albers, Jasper
and Babu, Pooja and Böttcher, Joshua and Mitchell, Jessica
and Wybo, Willem and Bruchertseifer, Jens and Spreizer,
Sebastian and Terhorst, Dennis},
title = {{F}rom single-cell modeling to large-scale network dynamics
with {NEST} {S}imulator},
reportid = {FZJ-2022-03260},
year = {2022},
abstract = {NEST is an established, open-source simulator for spiking
neuronal networks, which can capture a high degree of detail
of biological network structures while retaining high
performance and scalability from laptops to HPC [1]. This
tutorial provides hands-on experience in building and
simulating neuron, synapse, and network models. It
introduces several tools and front-ends to implement
modeling ideas most efficiently. Participants do not have to
install software as all tools can be accessed via the
cloud.First, we look at NEST Desktop [2], a web-based
graphical user interface (GUI), which allows the exploration
of essential concepts in computational neuroscience without
the need to learn a programming language. This advances both
the quality and speed of teaching in computational
neuroscience. To get acquainted with the GUI, we will create
and analyze abalanced two-population network.The model is
then exported to a Jupyter notebook and endowed with a
data-driven spatial connectivity profile of the cortex,
enabling us to study the propagation of activity. Then, we
make the synapses in the network plastic and let the network
learn a reinforcement learning task, whereby the learning
rule goes beyond pre-synaptic and post-synaptic spikes by
addinga dopamine signal as a modulatory third factor. NESTML
[3] makes it easy to express this and other advanced
synaptic plasticity rules and neuron models, and
automatically translates them into fast simulation code.More
morphologically detailed models, with a large number of
compartments and custom ion channels and receptor currents,
can also be defined using NESTML. We first implement a
simple dendritic layout and use it to perform a sequence
discrimination task. Next, we implement a compartmental
layout representing semi-independent subunits and
recurrentlyconnect several such neurons to elicit an
NMDA-spike driven network state.},
month = {Jul},
date = {2022-07-16},
organization = {31st Annual Computational Neuroscience
Meeting, CNS*2022, Melbourne
(Australia), 16 Jul 2022 - 20 Jul 2022},
subtyp = {Invited},
cin = {INM-6 / INM-10 / IAS-6 / JSC},
cid = {I:(DE-Juel1)INM-6-20090406 / I:(DE-Juel1)INM-10-20170113 /
I:(DE-Juel1)IAS-6-20130828 / I:(DE-Juel1)JSC-20090406},
pnm = {5235 - Digitization of Neuroscience and User-Community
Building (POF4-523) / 5231 - Neuroscientific Foundations
(POF4-523) / 5234 - Emerging NC Architectures (POF4-523) /
5111 - Domain-Specific Simulation $\&$ Data Life Cycle Labs
(SDLs) and Research Groups (POF4-511) / HBP SGA3 - Human
Brain Project Specific Grant Agreement 3 (945539) / SLNS -
SimLab Neuroscience (Helmholtz-SLNS)},
pid = {G:(DE-HGF)POF4-5235 / G:(DE-HGF)POF4-5231 /
G:(DE-HGF)POF4-5234 / G:(DE-HGF)POF4-5111 /
G:(EU-Grant)945539 / G:(DE-Juel1)Helmholtz-SLNS},
typ = {PUB:(DE-HGF)6},
url = {https://juser.fz-juelich.de/record/909578},
}