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| 001 | 909635 | ||
| 005 | 20230113085408.0 | ||
| 024 | 7 | _ | |a 10.3791/63304 |2 doi |
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| 024 | 7 | _ | |a WOS:000898056900010 |2 WOS |
| 037 | _ | _ | |a FZJ-2022-03306 |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Wieters, Frederique |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Terminal H-reflex Measurements in Mice |
| 260 | _ | _ | |a Cambridge, MA |c 2022 |b JoVE |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1670912701_32695 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a The Hoffmann reflex (H-reflex), as an electrical analog to the stretch reflex, allowselectrophysiological validation of the integrity of neural circuits after injuries such asspinal cord damage or stroke. An increase of the H-reflex response, together withsymptoms like non-voluntary muscle contractions, pathologically augmented stretchreflex, and hypertonia in the corresponding muscle, is an indicator of post-strokespasticity (PSS).In contrast to rather nerve-unspecific transcutaneous measurements, here, we presenta protocol to quantify the H-reflex directly at the ulnar and median nerves of theforepaw, which is applicable, with minor modifications, to the tibial and sciatic nerveof the hindpaw. Based on the direct stimulation and the adaptation to different nerves,the method represents a reliable and versatile tool to validate electrophysiologicalchanges in spasticity-related disease models. |
| 536 | _ | _ | |a 5251 - Multilevel Brain Organization and Variability (POF4-525) |0 G:(DE-HGF)POF4-5251 |c POF4-525 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, Journals: juser.fz-juelich.de |
| 700 | 1 | _ | |a Gruhn, Matthias |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Büschges, Ansgar |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Fink, Gereon R. |0 P:(DE-Juel1)131720 |b 3 |
| 700 | 1 | _ | |a Aswendt, Markus |0 P:(DE-HGF)0 |b 4 |e Corresponding author |
| 773 | _ | _ | |a 10.3791/63304 |g no. 184, p. 63304 |0 PERI:(DE-600)2975414-8 |n 184 |p 63304 |t JoVE science education |v . |y 2022 |x 1940-087X |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/909635/files/FINK__Wieters_2022_JoVE_Terminal%20H%20reflex%20Measurements%20in%20Mice.pdf |y Published on 2022-06-16. Available in OpenAccess from 2024-06-16. |
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