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000909955 1001_ $$0P:(DE-Juel1)131840$$aQaim, Syed M.$$b0$$ufzj
000909955 245__ $$aThe role of chemistry in accelerator-based production and separation of radionuclides as basis for radiolabelled compounds for medical applications
000909955 260__ $$aBerlin$$b˜Deœ Gruyter$$c2022
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000909955 520__ $$aRadiochemical separations used in large scale routine production of diagnostic and therapeutic radionuclides at a particle accelerator for patient care are briefly outlined. The role of chemistry at various stages of development of a production route of a novel radionuclide, namely nuclear data measurement, high-current targetry, chemical processing and quality control of the product, is discussed in detail. Special attention is paid to production of non-standard positron emitters (e.g. 44gSc, 64Cu, 68Ga, etc.) at a cyclotron and novel therapeutic radionuclides (e.g. 67Cu, 225Ac, etc.) at an accelerator. Some typical examples of radiochemical methods involved are presented.
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000909955 7001_ $$0P:(DE-Juel1)131849$$aSpahn, Ingo$$b1$$eCorresponding author$$ufzj
000909955 7001_ $$0P:(DE-Juel1)131846$$aScholten, Bernhard$$b2
000909955 7001_ $$0P:(DE-Juel1)131850$$aSpellerberg, Stefan$$b3$$ufzj
000909955 7001_ $$0P:(DE-Juel1)166419$$aNeumaier, Bernd$$b4$$ufzj
000909955 773__ $$0PERI:(DE-600)2039575-9$$a10.1515/ract-2022-0017$$gVol. 110, no. 6-9, p. 707 - 724$$n6-9$$p707 - 724$$tRadiochimica acta$$v110$$x0033-8230$$y2022
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