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@ARTICLE{Qaim:909955,
author = {Qaim, Syed M. and Spahn, Ingo and Scholten, Bernhard and
Spellerberg, Stefan and Neumaier, Bernd},
title = {{T}he role of chemistry in accelerator-based production and
separation of radionuclides as basis for radiolabelled
compounds for medical applications},
journal = {Radiochimica acta},
volume = {110},
number = {6-9},
issn = {0033-8230},
address = {Berlin},
publisher = {De Gruyter},
reportid = {FZJ-2022-03545},
pages = {707 - 724},
year = {2022},
abstract = {Radiochemical separations used in large scale routine
production of diagnostic and therapeutic radionuclides at a
particle accelerator for patient care are briefly outlined.
The role of chemistry at various stages of development of a
production route of a novel radionuclide, namely nuclear
data measurement, high-current targetry, chemical processing
and quality control of the product, is discussed in detail.
Special attention is paid to production of non-standard
positron emitters (e.g. 44gSc, 64Cu, 68Ga, etc.) at a
cyclotron and novel therapeutic radionuclides (e.g. 67Cu,
225Ac, etc.) at an accelerator. Some typical examples of
radiochemical methods involved are presented.},
cin = {INM-5},
ddc = {610},
cid = {I:(DE-Juel1)INM-5-20090406},
pnm = {5253 - Neuroimaging (POF4-525)},
pid = {G:(DE-HGF)POF4-5253},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000790949000001},
doi = {10.1515/ract-2022-0017},
url = {https://juser.fz-juelich.de/record/909955},
}