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100 1 _ |a Qaim, Syed M.
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245 _ _ |a The role of chemistry in accelerator-based production and separation of radionuclides as basis for radiolabelled compounds for medical applications
260 _ _ |a Berlin
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520 _ _ |a Radiochemical separations used in large scale routine production of diagnostic and therapeutic radionuclides at a particle accelerator for patient care are briefly outlined. The role of chemistry at various stages of development of a production route of a novel radionuclide, namely nuclear data measurement, high-current targetry, chemical processing and quality control of the product, is discussed in detail. Special attention is paid to production of non-standard positron emitters (e.g. 44gSc, 64Cu, 68Ga, etc.) at a cyclotron and novel therapeutic radionuclides (e.g. 67Cu, 225Ac, etc.) at an accelerator. Some typical examples of radiochemical methods involved are presented.
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700 1 _ |a Spahn, Ingo
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700 1 _ |a Scholten, Bernhard
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700 1 _ |a Spellerberg, Stefan
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700 1 _ |a Neumaier, Bernd
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773 _ _ |a 10.1515/ract-2022-0017
|g Vol. 110, no. 6-9, p. 707 - 724
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