TY - JOUR AU - Rodriguez, Nestor AU - Tiwari, Avinash AU - Persson, Bo TI - Air leakage in seals with application to syringes JO - Applied surface science advances VL - 8 SN - 2666-5239 CY - Amsterdam PB - Elsevier M1 - FZJ-2022-03889 SP - 100222 - PY - 2022 AB - We study the leakage of air in syringes with Teflon coated rubber stopper and glass barrel. The leakrate depends on the interfacial surface roughness, the viscoelastic properties of the rubber and on the elastoplastic properties of the Teflon coating. The measured leakage rates are compared to the predictions of a simple theory for gas flow, which takes into account both the diffusive and ballistic air flow, and the elastoplastic multiscale contact mechanics which determines the probability distribution of interfacial separations. The theory shows that the interfacial air flow (leakage) channels are so narrow that the gas flow is mainly ballistic (the so called Knudsen limit). The implications for container closure integrity is discussed. LB - PUB:(DE-HGF)16 UR - <Go to ISI:>//WOS:000768298900005 DO - DOI:10.1016/j.apsadv.2022.100222 UR - https://juser.fz-juelich.de/record/910506 ER -