000910587 001__ 910587
000910587 005__ 20230123125732.0
000910587 0247_ $$2doi$$a10.1523/JNEUROSCI.1522-21.2021
000910587 0247_ $$2ISSN$$a0270-6474
000910587 0247_ $$2ISSN$$a1529-2401
000910587 0247_ $$2Handle$$a2128/32359
000910587 0247_ $$2pmid$$a34969868
000910587 0247_ $$2WOS$$aWOS:000768775000001
000910587 037__ $$aFZJ-2022-03965
000910587 082__ $$a610
000910587 1001_ $$0P:(DE-HGF)0$$aLapate, Regina C.$$b0$$eCorresponding author
000910587 245__ $$aEmotional Context Sculpts Action Goal Representations in the Lateral Frontal Pole
000910587 260__ $$aWashington, DC$$bSoc.$$c2022
000910587 3367_ $$2DRIVER$$aarticle
000910587 3367_ $$2DataCite$$aOutput Types/Journal article
000910587 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1674463469_20587
000910587 3367_ $$2BibTeX$$aARTICLE
000910587 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000910587 3367_ $$00$$2EndNote$$aJournal Article
000910587 520__ $$aEmotional states provide an ever-present source of contextual information that should inform behavioral goals. Despite the ubiquity of emotional signals in our environment, the neural mechanisms underlying their influence on goal-directed action remains unclear. Prior work suggests that the lateral frontal pole (FPl) is uniquely positioned to integrate affective information into cognitive control representations. We used pattern similarity analysis to examine the content of representations in FPl and interconnected mid-lateral prefrontal and amygdala circuitry. Healthy participants (n = 37; n = 21 females) were scanned while undergoing an event-related Affective Go/No-Go task, which requires goal-oriented action selection during emotional processing. We found that FPl contained conjunctive emotion–action goal representations that were related to successful cognitive control during emotional processing. These representations differed from conjunctive emotion–action goal representations found in the basolateral amygdala. While robust action goal representations were present in mid-lateral prefrontal cortex, they were not modulated by emotional valence. Finally, converging results from functional connectivity and multivoxel pattern analyses indicated that FPl emotional valence signals likely originated from interconnected subgenual anterior cingulate cortex (ACC) (BA25), which was in turn functionally coupled with the amygdala. Thus, our results identify a key pathway by which internal emotional states influence goal-directed behavior.
000910587 536__ $$0G:(DE-HGF)POF4-5251$$a5251 - Multilevel Brain Organization and Variability (POF4-525)$$cPOF4-525$$fPOF IV$$x0
000910587 588__ $$aDataset connected to CrossRef, Journals: juser.fz-juelich.de
000910587 7001_ $$0P:(DE-HGF)0$$aBallard, Ian C.$$b1
000910587 7001_ $$0P:(DE-Juel1)173770$$aHeckner, Marisa K.$$b2$$ufzj
000910587 7001_ $$0P:(DE-HGF)0$$aD'Esposito, Mark$$b3
000910587 773__ $$0PERI:(DE-600)1475274-8$$a10.1523/JNEUROSCI.1522-21.2021$$gVol. 42, no. 8, p. 1529 - 1541$$n8$$p1529 - 1541$$tThe journal of neuroscience$$v42$$x0270-6474$$y2022
000910587 8564_ $$uhttps://juser.fz-juelich.de/record/910587/files/1529.full.pdf$$yPublished on 2022-02-23. Available in OpenAccess from 2022-08-23.
000910587 909CO $$ooai:juser.fz-juelich.de:910587$$popenaire$$pdnbdelivery$$pdriver$$pVDB$$popen_access
000910587 9101_ $$0I:(DE-HGF)0$$6P:(DE-HGF)0$$a University of California$$b0
000910587 9101_ $$0I:(DE-HGF)0$$6P:(DE-HGF)0$$a lapate@ucsb.edu$$b0
000910587 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)173770$$aForschungszentrum Jülich$$b2$$kFZJ
000910587 9131_ $$0G:(DE-HGF)POF4-525$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5251$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vDecoding Brain Organization and Dysfunction$$x0
000910587 9141_ $$y2022
000910587 915__ $$0StatID:(DE-HGF)0530$$2StatID$$aEmbargoed OpenAccess
000910587 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bJ NEUROSCI : 2021$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2022-11-13
000910587 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bJ NEUROSCI : 2021$$d2022-11-13
000910587 920__ $$lyes
000910587 9201_ $$0I:(DE-Juel1)INM-7-20090406$$kINM-7$$lGehirn & Verhalten$$x0
000910587 980__ $$ajournal
000910587 980__ $$aVDB
000910587 980__ $$aI:(DE-Juel1)INM-7-20090406
000910587 980__ $$aUNRESTRICTED
000910587 9801_ $$aFullTexts