000911711 001__ 911711
000911711 005__ 20230713203925.0
000911711 0247_ $$2doi$$a10.7554/eLife.77215
000911711 0247_ $$2Handle$$a2128/32755
000911711 0247_ $$2pmid$$a35904242
000911711 0247_ $$2WOS$$aWOS:000868281300001
000911711 0247_ $$2datacite_doi$$a10.34734/FZJ-2022-04963
000911711 037__ $$aFZJ-2022-04963
000911711 082__ $$a600
000911711 1001_ $$0P:(DE-Juel1)188407$$aWan, Bin$$b0$$eCorresponding author$$ufzj
000911711 245__ $$aHeritability and cross-species comparisons of human cortical functional organization asymmetry
000911711 260__ $$aCambridge$$beLife Sciences Publications$$c2022
000911711 3367_ $$2DRIVER$$aarticle
000911711 3367_ $$2DataCite$$aOutput Types/Journal article
000911711 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1689230066_4730
000911711 3367_ $$2BibTeX$$aARTICLE
000911711 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000911711 3367_ $$00$$2EndNote$$aJournal Article
000911711 520__ $$aThe human cerebral cortex is symmetrically organized along large-scale axes but also presents inter-hemispheric differences in structure and function. The quantified contralateral homologous difference, that is asymmetry, is a key feature of the human brain left-right axis supporting functional processes, such as language. Here, we assessed whether the asymmetry of cortical functional organization is heritable and phylogenetically conserved between humans and macaques. Our findings indicate asymmetric organization along an axis describing a functional trajectory from perceptual/action to abstract cognition. Whereas language network showed leftward asymmetric organization, frontoparietal network showed rightward asymmetric organization in humans. These asymmetries were heritable in humans and showed a similar spatial distribution with macaques, in the case of intra-hemispheric asymmetry of functional hierarchy. This suggests (phylo)genetic conservation. However, both language and frontoparietal networks showed a qualitatively larger asymmetry in humans relative to macaques. Overall, our findings suggest a genetic basis for asymmetry in intrinsic functional organization, linked to higher order cognitive functions uniquely developed in humans.
000911711 536__ $$0G:(DE-HGF)POF4-5252$$a5252 - Brain Dysfunction and Plasticity (POF4-525)$$cPOF4-525$$fPOF IV$$x0
000911711 588__ $$aDataset connected to CrossRef, Journals: juser.fz-juelich.de
000911711 7001_ $$0P:(DE-HGF)0$$aBayrak, Şeyma$$b1
000911711 7001_ $$0P:(DE-HGF)0$$aXu, Ting$$b2
000911711 7001_ $$0P:(DE-Juel1)188324$$aSchaare, H Lina$$b3
000911711 7001_ $$0P:(DE-HGF)0$$aBethlehem, Richard AI$$b4
000911711 7001_ $$0P:(DE-HGF)0$$aBernhardt, Boris C$$b5
000911711 7001_ $$0P:(DE-Juel1)173843$$aValk, Sofie L$$b6
000911711 773__ $$0PERI:(DE-600)2687154-3$$a10.7554/eLife.77215$$gVol. 11, p. e77215$$pe77215$$teLife$$v11$$x2050-084X$$y2022
000911711 8564_ $$uhttps://juser.fz-juelich.de/record/911711/files/Asymmetry%20of%20functional%20gradients_R2_clean.pdf$$yOpenAccess
000911711 8564_ $$uhttps://juser.fz-juelich.de/record/911711/files/elife-77215-v3.pdf$$yOpenAccess
000911711 909CO $$ooai:juser.fz-juelich.de:911711$$popenaire$$pdriver$$pVDB$$popen_access$$pdnbdelivery
000911711 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)188407$$aForschungszentrum Jülich$$b0$$kFZJ
000911711 9101_ $$0I:(DE-HGF)0$$6P:(DE-Juel1)188407$$a Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig$$b0
000911711 9101_ $$0I:(DE-HGF)0$$6P:(DE-HGF)0$$a Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig$$b1
000911711 9101_ $$0I:(DE-HGF)0$$6P:(DE-HGF)0$$a Center for the Developing Brain, Child Mind Institute, New York$$b2
000911711 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)188324$$aForschungszentrum Jülich$$b3$$kFZJ
000911711 9101_ $$0I:(DE-HGF)0$$6P:(DE-HGF)0$$a University of Cambridge,$$b4
000911711 9101_ $$0I:(DE-HGF)0$$6P:(DE-HGF)0$$a McGill University, Montréal, Canada$$b5
000911711 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)173843$$aForschungszentrum Jülich$$b6$$kFZJ
000911711 9101_ $$0I:(DE-HGF)0$$6P:(DE-Juel1)173843$$a Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig$$b6
000911711 9131_ $$0G:(DE-HGF)POF4-525$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5252$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vDecoding Brain Organization and Dysfunction$$x0
000911711 9141_ $$y2022
000911711 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2022-11-23
000911711 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2022-11-23
000911711 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2022-11-23
000911711 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2021-02-03
000911711 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2022-11-23
000911711 915__ $$0StatID:(DE-HGF)1040$$2StatID$$aDBCoverage$$bZoological Record$$d2022-11-23
000911711 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bELIFE : 2021$$d2022-11-23
000911711 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-02-03
000911711 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2022-09-23T12:20:44Z
000911711 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-02-03
000911711 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2022-09-23T12:20:44Z
000911711 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2021-02-03
000911711 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000911711 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2022-11-23
000911711 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2021-02-03
000911711 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bELIFE : 2021$$d2022-11-23
000911711 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2022-11-23
000911711 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000911711 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2022-11-23
000911711 920__ $$lyes
000911711 9201_ $$0I:(DE-Juel1)INM-7-20090406$$kINM-7$$lGehirn & Verhalten$$x0
000911711 980__ $$ajournal
000911711 980__ $$aVDB
000911711 980__ $$aUNRESTRICTED
000911711 980__ $$aI:(DE-Juel1)INM-7-20090406
000911711 9801_ $$aFullTexts