TY  - CONF
AU  - Friedrich, Patrick
AU  - Patil, Kaustubh
AU  - Mochalski, Lisa
AU  - Li, Xuan
AU  - Camilleri, Julia
AU  - Kröll, Jean-Philippe
AU  - Wiersch, Lisa
AU  - Vickery, Sam
AU  - Hopkins, William D.
AU  - Hoffstaedter, Felix
AU  - Eickhoff, Simon
AU  - Weis, Susanne
TI  - Is it left or is it right? A machine learning framework for studying hemispheric differences
M1  - FZJ-2022-05003
PY  - 2022
AB  - The comparison between regions or tracts in the left and right hemispheres grants insight into localasymmetries as one characteristic feature of brain organization. These pairwise comparisons,however, are reminiscent of a localists’ view and come with several caveats when assessing multipleasymmetries. To overcome some of the limitations set by conventional statistical comparisons, werecently introduced a novel machine learning-based framework for studying hemispheric differences.In a recent proof-of-principle study, we showed the capability of machine learning-based classificationto distinguish the hemispheres based on voxel-wise features. Using a Boruta feature-selectionalgorithm allowed the mapping of voxels that were important for correctly classifying a givenhemisphere. Furthermore, relating these maps of hemisphere-determining voxels with volumetricasymmetries validated our approach for mapping lateralized brain structure. In this talk, I will highlightour framework for studying hemispheric differences and present ongoing work on possibleapplications.
T2  - 8th North Sea Laterality Conference on Brain Asymmetry
CY  - 24 Aug 2022 - 27 Aug 2022, Bergen (Norway)
Y2  - 24 Aug 2022 - 27 Aug 2022
M2  - Bergen, Norway
LB  - PUB:(DE-HGF)6
UR  - https://juser.fz-juelich.de/record/911751
ER  -