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@INPROCEEDINGS{Friedrich:911751,
      author       = {Friedrich, Patrick and Patil, Kaustubh and Mochalski, Lisa
                      and Li, Xuan and Camilleri, Julia and Kröll, Jean-Philippe
                      and Wiersch, Lisa and Vickery, Sam and Hopkins, William D.
                      and Hoffstaedter, Felix and Eickhoff, Simon and Weis,
                      Susanne},
      title        = {{I}s it left or is it right? {A} machine learning framework
                      for studying hemispheric differences},
      reportid     = {FZJ-2022-05003},
      year         = {2022},
      abstract     = {The comparison between regions or tracts in the left and
                      right hemispheres grants insight into localasymmetries as
                      one characteristic feature of brain organization. These
                      pairwise comparisons,however, are reminiscent of a
                      localists’ view and come with several caveats when
                      assessing multipleasymmetries. To overcome some of the
                      limitations set by conventional statistical comparisons,
                      werecently introduced a novel machine learning-based
                      framework for studying hemispheric differences.In a recent
                      proof-of-principle study, we showed the capability of
                      machine learning-based classificationto distinguish the
                      hemispheres based on voxel-wise features. Using a Boruta
                      feature-selectionalgorithm allowed the mapping of voxels
                      that were important for correctly classifying a
                      givenhemisphere. Furthermore, relating these maps of
                      hemisphere-determining voxels with volumetricasymmetries
                      validated our approach for mapping lateralized brain
                      structure. In this talk, I will highlightour framework for
                      studying hemispheric differences and present ongoing work on
                      possibleapplications.},
      month         = {Aug},
      date          = {2022-08-24},
      organization  = {8th North Sea Laterality Conference on
                       Brain Asymmetry, Bergen (Norway), 24
                       Aug 2022 - 27 Aug 2022},
      subtyp        = {Invited},
      cin          = {INM-7},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)6},
      url          = {https://juser.fz-juelich.de/record/911751},
}