001     911751
005     20221123131044.0
037 _ _ |a FZJ-2022-05003
100 1 _ |a Friedrich, Patrick
|0 P:(DE-Juel1)185938
|b 0
111 2 _ |a 8th North Sea Laterality Conference on Brain Asymmetry
|c Bergen
|d 2022-08-24 - 2022-08-27
|w Norway
245 _ _ |a Is it left or is it right? A machine learning framework for studying hemispheric differences
260 _ _ |c 2022
336 7 _ |a Conference Paper
|0 33
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336 7 _ |a Conference Presentation
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520 _ _ |a The comparison between regions or tracts in the left and right hemispheres grants insight into localasymmetries as one characteristic feature of brain organization. These pairwise comparisons,however, are reminiscent of a localists’ view and come with several caveats when assessing multipleasymmetries. To overcome some of the limitations set by conventional statistical comparisons, werecently introduced a novel machine learning-based framework for studying hemispheric differences.In a recent proof-of-principle study, we showed the capability of machine learning-based classificationto distinguish the hemispheres based on voxel-wise features. Using a Boruta feature-selectionalgorithm allowed the mapping of voxels that were important for correctly classifying a givenhemisphere. Furthermore, relating these maps of hemisphere-determining voxels with volumetricasymmetries validated our approach for mapping lateralized brain structure. In this talk, I will highlightour framework for studying hemispheric differences and present ongoing work on possibleapplications.
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700 1 _ |a Patil, Kaustubh
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700 1 _ |a Mochalski, Lisa
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700 1 _ |a Li, Xuan
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700 1 _ |a Camilleri, Julia
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700 1 _ |a Kröll, Jean-Philippe
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700 1 _ |a Wiersch, Lisa
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700 1 _ |a Vickery, Sam
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700 1 _ |a Hopkins, William D.
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700 1 _ |a Hoffstaedter, Felix
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700 1 _ |a Eickhoff, Simon
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700 1 _ |a Weis, Susanne
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914 1 _ |y 2022
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Marc 21