%0 Journal Article
%A Maity, Debabrata
%A Oh, Yujeong
%A Gremer, Lothar
%A Hoyer, Wolfgang
%A Magzoub, Mazin
%A Hamilton, Andrew D
%T Cucurbit[7]uril Inhibits Islet Amyloid Polypeptide Aggregation by Targeting N Terminus Hot Segments and Attenuates Cytotoxicity.
%J Chemistry - a European journal
%V 28
%N 38
%@ 0947-6539
%C Weinheim
%I Wiley-VCH
%M FZJ-2022-05395
%P na/na
%D 2022
%X Invited for the cover of this issue is the group of Prof. Hamilton at New York University. The image depicts how cucurbit[7]uril inhibits islet amyloid polypeptide self-assembly that rescues rat insulinoma cells (a pancreatic β-cell model) from assembly-associated cytotoxicity. Read the full text of the article at 10.1002/chem.202200456.
%K Amyloid
%K Animals
%K Bridged-Ring Compounds: pharmacology
%K Heterocyclic Compounds, 2-Ring
%K Humans
%K Imidazoles: pharmacology
%K Imidazolidines
%K Insulin-Secreting Cells
%K Islet Amyloid Polypeptide
%K Macrocyclic Compounds
%K Rats
%K Amyloid (NLM Chemicals)
%K Bridged-Ring Compounds (NLM Chemicals)
%K Heterocyclic Compounds, 2-Ring (NLM Chemicals)
%K Imidazoles (NLM Chemicals)
%K Imidazolidines (NLM Chemicals)
%K Islet Amyloid Polypeptide (NLM Chemicals)
%K Macrocyclic Compounds (NLM Chemicals)
%K cucurbit(7)uril (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:35701098
%U <Go to ISI:>//WOS:000810702900001
%R 10.1002/chem.202201698
%U https://juser.fz-juelich.de/record/912179