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@ARTICLE{Nikolaev:912399,
      author       = {Nikolaev, K. G. and Ermakov, S. S. and Ermolenko, Yu. E.
                      and Navolotskaya, D. V. and Offenhäusser, A. and Mourzina,
                      Youlia},
      title        = {{H}orseradish {P}eroxidase-{B}ased {B}iosensors with
                      {D}ifferent {N}anotransducers for the {D}etermination of
                      {H}ydrogen {P}eroxide},
      journal      = {Journal of analytical chemistry},
      volume       = {76},
      number       = {4},
      issn         = {1061-9348},
      address      = {Dordrecht [u.a.]},
      publisher    = {Springer Science + Business Media B.V},
      reportid     = {FZJ-2022-05584},
      pages        = {510 - 517},
      year         = {2021},
      abstract     = {We studied methods of the in situ synthesis of gold
                      nanostructures on the electrode surface and of the directed
                      electrochemical synthesis of nanodendrites to create
                      biosensors based on horseradish peroxidase. The effect of
                      nanostructuring of the transducer surface and its subsequent
                      modification on the electroanalytical characteristics of
                      sensors for the determination of hydrogen peroxide was
                      studied. The use of these methods can significantly improve
                      the performance characteristics of the biosensors, such as
                      the sensitivity coefficient, limit of detection, and
                      stability in the range of micromolar and submicromolar
                      concentrations of hydrogen peroxide. The electrodes modified
                      by the in situ synthesis of nanostructures with subsequent
                      treatment with Meerwein’s reagent, as well as
                      ultramicroelectrodes prepared by directional electrochemical
                      synthesis, show low limits of detection for hydrogen
                      peroxide, 0.2 and 0.08 µM, and high sensitivity
                      coefficients, 0.71 and 0.84 A M–1 cm–2, respectively.},
      cin          = {IBI-3},
      ddc          = {540},
      cid          = {I:(DE-Juel1)IBI-3-20200312},
      pnm          = {5241 - Molecular Information Processing in Cellular Systems
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-5241},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000640197200011},
      doi          = {10.1134/S1061934821040080},
      url          = {https://juser.fz-juelich.de/record/912399},
}