000912526 001__ 912526
000912526 005__ 20230123110758.0
000912526 0247_ $$2doi$$a10.1038/s41746-022-00677-8
000912526 0247_ $$2Handle$$a2128/33089
000912526 0247_ $$2pmid$$a36109583
000912526 0247_ $$2WOS$$aWOS:000854756700001
000912526 037__ $$aFZJ-2022-05699
000912526 082__ $$a610
000912526 1001_ $$0P:(DE-HGF)0$$aKambeitz-Ilankovic, Lana$$b0
000912526 245__ $$aA systematic review of digital and face-to-face cognitive behavioral therapy for depression
000912526 260__ $$a[Basingstoke]$$bMacmillan Publishers Limited$$c2022
000912526 3367_ $$2DRIVER$$aarticle
000912526 3367_ $$2DataCite$$aOutput Types/Journal article
000912526 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1670999186_23230
000912526 3367_ $$2BibTeX$$aARTICLE
000912526 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000912526 3367_ $$00$$2EndNote$$aJournal Article
000912526 520__ $$aCognitive behavioral therapy (CBT) represents one of the major treatment options for depressive disorders besides pharmacological interventions. While newly developed digital CBT approaches hold important advantages due to higher accessibility, their relative effectiveness compared to traditional CBT remains unclear. We conducted a systematic literature search to identify all studies that conducted a CBT-based intervention (face-to-face or digital) in patients with major depression. Random-effects meta-analytic models of the standardized mean change using raw score standardization (SMCR) were computed. In 106 studies including n = 11854 patients face-to-face CBT shows superior clinical effectiveness compared to digital CBT when investigating depressive symptoms (p < 0.001, face-to-face CBT: SMCR = 1.97, 95%-CI: 1.74–2.13, digital CBT: SMCR = 1.20, 95%-CI: 1.08–1.32) and adherence (p = 0.014, face-to-face CBT: 82.4%, digital CBT: 72.9%). However, after accounting for differences between face-to-face and digital CBT studies, both approaches indicate similar effectiveness. Important variables with significant moderation effects include duration of the intervention, baseline severity, adherence and the level of human guidance in digital CBT interventions. After accounting for potential confounders our analysis indicates comparable effectiveness of face-to-face and digital CBT approaches. These findings underline the importance of moderators of clinical effects and provide a basis for the future personalization of CBT treatment in depression.Subject terms: Depression, Randomized controlled trials
000912526 536__ $$0G:(DE-HGF)POF4-5251$$a5251 - Multilevel Brain Organization and Variability (POF4-525)$$cPOF4-525$$fPOF IV$$x0
000912526 588__ $$aDataset connected to CrossRef, Journals: juser.fz-juelich.de
000912526 7001_ $$0P:(DE-HGF)0$$aRzayeva, Uma$$b1
000912526 7001_ $$0P:(DE-HGF)0$$aVölkel, Laura$$b2
000912526 7001_ $$0P:(DE-HGF)0$$aWenzel, Julian$$b3
000912526 7001_ $$0P:(DE-HGF)0$$aWeiske, Johanna$$b4
000912526 7001_ $$0P:(DE-HGF)0$$aJessen, Frank$$b5
000912526 7001_ $$0P:(DE-HGF)0$$aReininghaus, Ulrich$$b6
000912526 7001_ $$0P:(DE-HGF)0$$aUhlhaas, Peter J.$$b7
000912526 7001_ $$0P:(DE-HGF)0$$aAlvarez-Jimenez, Mario$$b8
000912526 7001_ $$0P:(DE-Juel1)188257$$aKambeitz, Joseph$$b9$$eCorresponding author
000912526 773__ $$0PERI:(DE-600)2925182-5$$a10.1038/s41746-022-00677-8$$gVol. 5, no. 1, p. 144$$n1$$p144$$tnpj digital medicine$$v5$$x2398-6352$$y2022
000912526 8564_ $$uhttps://juser.fz-juelich.de/record/912526/files/PDF.pdf$$yOpenAccess
000912526 909CO $$ooai:juser.fz-juelich.de:912526$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
000912526 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)188257$$aForschungszentrum Jülich$$b9$$kFZJ
000912526 9131_ $$0G:(DE-HGF)POF4-525$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5251$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vDecoding Brain Organization and Dysfunction$$x0
000912526 9141_ $$y2022
000912526 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000912526 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2020-08-28
000912526 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000912526 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2020-08-28
000912526 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2022-11-18
000912526 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2022-11-18
000912526 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2021-10-13T14:28:38Z
000912526 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2021-10-13T14:28:38Z
000912526 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Blind peer review$$d2021-10-13T14:28:38Z
000912526 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2022-11-18
000912526 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2022-11-18
000912526 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2022-11-18
000912526 920__ $$lyes
000912526 9201_ $$0I:(DE-Juel1)INM-3-20090406$$kINM-3$$lKognitive Neurowissenschaften$$x0
000912526 980__ $$ajournal
000912526 980__ $$aVDB
000912526 980__ $$aUNRESTRICTED
000912526 980__ $$aI:(DE-Juel1)INM-3-20090406
000912526 9801_ $$aFullTexts