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000916075 1001_ $$0P:(DE-Juel1)165189$$aShokoohimehr, Pegah$$b0
000916075 245__ $$aHigh‐Aspect‐Ratio Nanoelectrodes Enable Long‐Term Recordings of Neuronal Signals with Subthreshold Resolution
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000916075 520__ $$aThe further development of neurochips requires high-density and high-resolution recordings that also allow neuronal signals to be observed over a long period of time. Expanding fields of network neuroscience and neuromorphic engineering demand the multiparallel and direct estimations of synaptic weights, and the key objective is to construct a device that also records subthreshold events. Recently, 3D nanostructures with a high aspect ratio have become a particularly suitable interface between neurons and electronic devices, since the excellent mechanical coupling to the neuronal cell membrane allows very high signal-to-noise ratio recordings. In the light of an increasing demand for a stable, noninvasive and long-term recording at subthreshold resolution, a combination of vertical nanostraws with nanocavities is presented. These structures provide a spontaneous tight coupling with rat cortical neurons, resulting in high amplitude sensitivity and postsynaptic resolution capability, as directly confirmed by combined patch-clamp and microelectrode array measurements.
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000916075 7001_ $$0P:(DE-Juel1)180680$$aCepkenovic, Bogdana$$b1
000916075 7001_ $$0P:(DE-Juel1)169481$$aMilos, Frano$$b2
000916075 7001_ $$0P:(DE-Juel1)187129$$aBednár, Justus$$b3
000916075 7001_ $$0P:(DE-Juel1)165980$$aHassani, Hossein$$b4
000916075 7001_ $$0P:(DE-Juel1)128705$$aMaybeck, Vanessa$$b5
000916075 7001_ $$0P:(DE-Juel1)128713$$aOffenhäusser, Andreas$$b6$$eCorresponding author
000916075 773__ $$0PERI:(DE-600)2168935-0$$a10.1002/smll.202200053$$gVol. 18, no. 22, p. 2200053 -$$n22$$p2200053 -$$tSmall$$v18$$x1613-6810$$y2022
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