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@ARTICLE{Shokoohimehr:916075,
author = {Shokoohimehr, Pegah and Cepkenovic, Bogdana and Milos,
Frano and Bednár, Justus and Hassani, Hossein and Maybeck,
Vanessa and Offenhäusser, Andreas},
title = {{H}igh‐{A}spect‐{R}atio {N}anoelectrodes {E}nable
{L}ong‐{T}erm {R}ecordings of {N}euronal {S}ignals with
{S}ubthreshold {R}esolution},
journal = {Small},
volume = {18},
number = {22},
issn = {1613-6810},
address = {Weinheim},
publisher = {Wiley-VCH},
reportid = {FZJ-2022-05921},
pages = {2200053 -},
year = {2022},
abstract = {The further development of neurochips requires high-density
and high-resolution recordings that also allow neuronal
signals to be observed over a long period of time. Expanding
fields of network neuroscience and neuromorphic engineering
demand the multiparallel and direct estimations of synaptic
weights, and the key objective is to construct a device that
also records subthreshold events. Recently, 3D
nanostructures with a high aspect ratio have become a
particularly suitable interface between neurons and
electronic devices, since the excellent mechanical coupling
to the neuronal cell membrane allows very high
signal-to-noise ratio recordings. In the light of an
increasing demand for a stable, noninvasive and long-term
recording at subthreshold resolution, a combination of
vertical nanostraws with nanocavities is presented. These
structures provide a spontaneous tight coupling with rat
cortical neurons, resulting in high amplitude sensitivity
and postsynaptic resolution capability, as directly
confirmed by combined patch-clamp and microelectrode array
measurements.},
cin = {IBI-3},
ddc = {620},
cid = {I:(DE-Juel1)IBI-3-20200312},
pnm = {5241 - Molecular Information Processing in Cellular Systems
(POF4-524)},
pid = {G:(DE-HGF)POF4-5241},
typ = {PUB:(DE-HGF)16},
pubmed = {35527345},
UT = {WOS:000792050700001},
doi = {10.1002/smll.202200053},
url = {https://juser.fz-juelich.de/record/916075},
}