Home > Publications database > High‐Aspect‐Ratio Nanoelectrodes Enable Long‐Term Recordings of Neuronal Signals with Subthreshold Resolution > print |
001 | 916075 | ||
005 | 20230227201810.0 | ||
024 | 7 | _ | |a 10.1002/smll.202200053 |2 doi |
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100 | 1 | _ | |a Shokoohimehr, Pegah |0 P:(DE-Juel1)165189 |b 0 |
245 | _ | _ | |a High‐Aspect‐Ratio Nanoelectrodes Enable Long‐Term Recordings of Neuronal Signals with Subthreshold Resolution |
260 | _ | _ | |a Weinheim |c 2022 |b Wiley-VCH |
336 | 7 | _ | |a article |2 DRIVER |
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520 | _ | _ | |a The further development of neurochips requires high-density and high-resolution recordings that also allow neuronal signals to be observed over a long period of time. Expanding fields of network neuroscience and neuromorphic engineering demand the multiparallel and direct estimations of synaptic weights, and the key objective is to construct a device that also records subthreshold events. Recently, 3D nanostructures with a high aspect ratio have become a particularly suitable interface between neurons and electronic devices, since the excellent mechanical coupling to the neuronal cell membrane allows very high signal-to-noise ratio recordings. In the light of an increasing demand for a stable, noninvasive and long-term recording at subthreshold resolution, a combination of vertical nanostraws with nanocavities is presented. These structures provide a spontaneous tight coupling with rat cortical neurons, resulting in high amplitude sensitivity and postsynaptic resolution capability, as directly confirmed by combined patch-clamp and microelectrode array measurements. |
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700 | 1 | _ | |a Cepkenovic, Bogdana |0 P:(DE-Juel1)180680 |b 1 |
700 | 1 | _ | |a Milos, Frano |0 P:(DE-Juel1)169481 |b 2 |
700 | 1 | _ | |a Bednár, Justus |0 P:(DE-Juel1)187129 |b 3 |
700 | 1 | _ | |a Hassani, Hossein |0 P:(DE-Juel1)165980 |b 4 |
700 | 1 | _ | |a Maybeck, Vanessa |0 P:(DE-Juel1)128705 |b 5 |
700 | 1 | _ | |a Offenhäusser, Andreas |0 P:(DE-Juel1)128713 |b 6 |e Corresponding author |
773 | _ | _ | |a 10.1002/smll.202200053 |g Vol. 18, no. 22, p. 2200053 - |0 PERI:(DE-600)2168935-0 |n 22 |p 2200053 - |t Small |v 18 |y 2022 |x 1613-6810 |
856 | 4 | _ | |y OpenAccess |u https://juser.fz-juelich.de/record/916075/files/Re-revised%20manuscript%20Nanostraw%20Nanocavity%20MEA.pdf |
856 | 4 | _ | |y OpenAccess |u https://juser.fz-juelich.de/record/916075/files/Small%20-%202022%20-%20Shokoohimehr%20-%20High%E2%80%90Aspect%E2%80%90Ratio%20Nanoelectrodes%20Enable%20Long%E2%80%90Term%20Recordings%20of%20Neuronal%20Signals%20with.pdf |
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