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000916201 041__ $$aEnglish
000916201 1001_ $$0P:(DE-Juel1)171932$$aStella, Alessandra$$b0$$eCorresponding author$$ufzj
000916201 1112_ $$aVisit to University of Berkeley$$d2022-11-21 - 2022-11-21$$wUSA
000916201 245__ $$aMultiple Overlapping Cell Assemblies Active During Motor Behavior$$f2022-11-21 -
000916201 260__ $$c2022
000916201 3367_ $$033$$2EndNote$$aConference Paper
000916201 3367_ $$2DataCite$$aOther
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000916201 520__ $$aThe cell assembly hypothesis postulates that information processing in the brain entails the repetitive co-activation of groups of neurons [1]. The activation of such assemblies would lead to spatio-temporal spike patterns (STPs) at the resolution of a few milliseconds. In order to test the cell assembly hypothesis, we searched for significant STPs in parallel spike trains, using the SPADE method [2,3]. We analyzed experimental data from the motor cortex (M1/PMd) of macaque monkeys (Macaca mulatta) performing a reach-to-grasp task [4] and found an abundance of STPs. Quantitative analysis showed that STPs are functionally related to behavior, which suggests the presence of assemblies activated during the task.References:[1] Hebb, D. O. (1949). John Wiley & Sons[2] Stella et al. (2019). Biosystems, 185, 104022. [doi: 10.1016/j.biosystems.2019.104022][3] Stella et al. (2022). eNeuro [doi: 10.1523/ENEURO.0505-21.2022][4] Brochier et al. (2018). Scientific data 5.1: 1-23. [doi: 10.12751/g-node.f83565]
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000916201 7001_ $$0P:(DE-Juel1)144168$$aGrün, Sonja$$b1$$ufzj
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000916201 9141_ $$y2022
000916201 9201_ $$0I:(DE-Juel1)INM-6-20090406$$kINM-6$$lComputational and Systems Neuroscience$$x0
000916201 9201_ $$0I:(DE-Juel1)IAS-6-20130828$$kIAS-6$$lTheoretical Neuroscience$$x1
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