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@ARTICLE{KorcsakGorzo:916425,
author = {Korcsak-Gorzo, Agnes and Linssen, Charl and Albers, Jasper
and Dasbach, Stefan and Duarte, Renato and Kunkel, Susanne
and Morrison, Abigail and Senk, Johanna and Stapmanns, Jonas
and Tetzlaff, Tom and Diesmann, Markus and van Albada, Sacha
J.},
title = {{P}henomenological modeling of diverse and heterogeneous
synaptic dynamics at natural density},
journal = {arXiv},
publisher = {arXiv},
reportid = {FZJ-2022-06225},
year = {2022},
abstract = {This chapter sheds light on the synaptic organization of
the brain from the perspective of computational
neuroscience. It provides an introductory overview on how to
account for empirical data in mathematical models, implement
them in software, and perform simulations reflecting
experiments. This path is demonstrated with respect to four
key aspects of synaptic signaling: the connectivity of brain
networks, synaptic transmission, synaptic plasticity, and
the heterogeneity across synapses. Each step and aspect of
the modeling and simulation workflow comes with its own
challenges and pitfalls, which are highlighted and addressed
in detail.},
keywords = {Neurons and Cognition (q-bio.NC) (Other) / Neural and
Evolutionary Computing (cs.NE) (Other) / FOS: Biological
sciences (Other) / FOS: Computer and information sciences
(Other)},
cin = {INM-6 / IAS-6 / INM-10 / JSC / IEK-4 / PGI-15},
cid = {I:(DE-Juel1)INM-6-20090406 / I:(DE-Juel1)IAS-6-20130828 /
I:(DE-Juel1)INM-10-20170113 / I:(DE-Juel1)JSC-20090406 /
I:(DE-Juel1)IEK-4-20101013 / I:(DE-Juel1)PGI-15-20210701},
pnm = {5231 - Neuroscientific Foundations (POF4-523) / HBP SGA3 -
Human Brain Project Specific Grant Agreement 3 (945539) / JL
SMHB - Joint Lab Supercomputing and Modeling for the Human
Brain (JL SMHB-2021-2027) / ACA - Advanced Computing
Architectures (SO-092) / BMBF-03ZU1106CB - NeuroSys:
Algorithm-Hardware Co-Design (Projekt C) - B
(BMBF-03ZU1106CB) / Helmholtz Platform for Research Software
Engineering - Preparatory Study $(HiRSE_PS-20220812)$},
pid = {G:(DE-HGF)POF4-5231 / G:(EU-Grant)945539 / G:(DE-Juel1)JL
SMHB-2021-2027 / G:(DE-HGF)SO-092 /
G:(DE-Juel1)BMBF-03ZU1106CB /
$G:(DE-Juel-1)HiRSE_PS-20220812$},
typ = {PUB:(DE-HGF)25},
doi = {10.48550/ARXIV.2212.05354},
url = {https://juser.fz-juelich.de/record/916425},
}