000917292 001__ 917292 000917292 005__ 20240712084621.0 000917292 0247_ $$2doi$$a10.1039/D2NJ05663A 000917292 0247_ $$2WOS$$aWOS:000913958300001 000917292 0247_ $$2Handle$$a2128/34082 000917292 037__ $$aFZJ-2023-00522 000917292 041__ $$aEnglish 000917292 082__ $$a540 000917292 1001_ $$0P:(DE-Juel1)190476$$aDiaz Gomez, Laura Johana$$b0$$ufzj 000917292 245__ $$aSynthesis and evaluation of new modified diglycolamides with different stereochemistry for extraction of tri- and tetravalent metal ions 000917292 260__ $$aLondon$$bRSC$$c2023 000917292 3367_ $$2DRIVER$$aarticle 000917292 3367_ $$2DataCite$$aOutput Types/Journal article 000917292 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1678449383_17941 000917292 3367_ $$2BibTeX$$aARTICLE 000917292 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000917292 3367_ $$00$$2EndNote$$aJournal Article 000917292 520__ $$aAmericium separation from high level nuclear waste can provide certain benefits such as reducing the long-term heat generation or the possibility of re-use as fuel in innovative reactors. The separation is carried out through solvent extraction. Among commonly used ligands, diglycolamide (DGA) derivatives have shown high distribution ratios for trivalent lanthanides (Ln(III)) and actinides (An(III)). Recently, different diastereomers of DGAs with substitutions in the backbone have shown an inverse selectivity for Am over Cm, in comparison with commonly used DGAs. Hence, we synthesised, characterized, and tested novel <i>syn</i>- and <i>anti</i>-diastereomers of tetra-<i>n</i>-octyl and tetra-<i>n</i>-decyl DGAs with two propyl and ethyl-methyl substituents at the backbone methylene carbon atoms. The distribution ratios for An(III) and Ln(III) were found to be generally lower than for the unsubstituted parent molecules due to steric hindrance. On the other hand, <sup>239</sup>Pu was much better extracted. All tested ligands showed the inverse selectivity for Am with an Am/Cm separation factor (SF<sub>Am/Cm</sub>) around 1.5. 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