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000009710 0247_ $$2DOI$$a10.1093/cercor/bhp208
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000009710 084__ $$2WoS$$aNeurosciences
000009710 1001_ $$0P:(DE-Juel1)VDB67936$$aKurth, F.$$b0$$uFZJ
000009710 245__ $$aCytoarchitecture and Probabilistic Maps of the Human Posterior Insular Cortex.
000009710 260__ $$aOxford$$bOxford Univ. Press$$c2010
000009710 300__ $$a1448 - 1461
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000009710 440_0 $$01171$$aCerebral Cortex$$v20$$x1047-3211$$y6
000009710 500__ $$aHuman Brain Project/Neuroinformatics research by the National Institute of Biomedical Imaging and Bioengineering; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Helmholtz Alliance "Systems Biology" the "Human Brain Model" (WP02 P03 to K. Z. and S. E.).
000009710 520__ $$aThe human posterior insula was shown to respond to a wide variety of stimulation paradigms (e.g. pain, somatosensory, or auditory processing) in functional imaging experiments. Although various anatomical maps of this region have been published over the last century, these schemes show variable results. Moreover, none can directly be integrated with functional imaging data. Hence, our current knowledge about the structure-function relationships in this region remains limited. We therefore remapped the posterior part of the human insular cortex in 10 postmortem brains using an observer-independent approach. This analysis revealed the existence of 3 cytoarchitectonically distinct areas in the posterior insula. The examined brains were then 3D reconstructed and spatially normalized to the Montreal Neurological Institute single-subject template. Probabilistic maps for each area were calculated by superimposing the individual delineations, and a cytoarchitectonic summary map was computed to chart the regional architectonic organization. These maps can be used to identify the anatomical correlates of functional activations observed in neuroimaging studies and to understand the microstructural correlates of the functional segregation of the human posterior insula.
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000009710 65320 $$2Author$$adysgranular
000009710 65320 $$2Author$$agranular
000009710 65320 $$2Author$$amicrostructure
000009710 65320 $$2Author$$asensory
000009710 650_2 $$2MeSH$$aAdult
000009710 650_2 $$2MeSH$$aAged
000009710 650_2 $$2MeSH$$aAged, 80 and over
000009710 650_2 $$2MeSH$$aBrain Mapping: methods
000009710 650_2 $$2MeSH$$aCerebral Cortex: cytology
000009710 650_2 $$2MeSH$$aCerebral Cortex: physiology
000009710 650_2 $$2MeSH$$aFemale
000009710 650_2 $$2MeSH$$aFunctional Laterality: physiology
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000009710 650_2 $$2MeSH$$aNerve Fibers, Myelinated: physiology
000009710 650_2 $$2MeSH$$aNeural Pathways: anatomy & histology
000009710 650_2 $$2MeSH$$aNeural Pathways: cytology
000009710 650_2 $$2MeSH$$aNeural Pathways: physiology
000009710 650_2 $$2MeSH$$aNeurons: cytology
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000009710 7001_ $$0P:(DE-Juel1)131678$$aEickhoff, S. B.$$b1$$uFZJ
000009710 7001_ $$0P:(DE-HGF)0$$aSchleicher, A.$$b2
000009710 7001_ $$0P:(DE-Juel1)VDB33804$$aHoemke, L.$$b3$$uFZJ
000009710 7001_ $$0P:(DE-Juel1)131714$$aZilles, K.$$b4$$uFZJ
000009710 7001_ $$0P:(DE-Juel1)131631$$aAmunts, K.$$b5$$uFZJ
000009710 773__ $$0PERI:(DE-600)1483485-6$$a10.1093/cercor/bhp208$$gVol. 20, p. 1448 - 1461$$p1448 - 1461$$q20<1448 - 1461$$tCerebral cortex$$v20$$x1047-3211$$y2010
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