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@ARTICLE{Kurth:9710,
      author       = {Kurth, F. and Eickhoff, S. B. and Schleicher, A. and
                      Hoemke, L. and Zilles, K. and Amunts, K.},
      title        = {{C}ytoarchitecture and {P}robabilistic {M}aps of the
                      {H}uman {P}osterior {I}nsular {C}ortex.},
      journal      = {Cerebral cortex},
      volume       = {20},
      issn         = {1047-3211},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {PreJuSER-9710},
      pages        = {1448 - 1461},
      year         = {2010},
      note         = {Human Brain Project/Neuroinformatics research by the
                      National Institute of Biomedical Imaging and Bioengineering;
                      National Institute of Neurological Disorders and Stroke;
                      National Institute of Mental Health; Helmholtz Alliance
                      "Systems Biology" the "Human Brain Model" (WP02 P03 to K. Z.
                      and S. E.).},
      abstract     = {The human posterior insula was shown to respond to a wide
                      variety of stimulation paradigms (e.g. pain, somatosensory,
                      or auditory processing) in functional imaging experiments.
                      Although various anatomical maps of this region have been
                      published over the last century, these schemes show variable
                      results. Moreover, none can directly be integrated with
                      functional imaging data. Hence, our current knowledge about
                      the structure-function relationships in this region remains
                      limited. We therefore remapped the posterior part of the
                      human insular cortex in 10 postmortem brains using an
                      observer-independent approach. This analysis revealed the
                      existence of 3 cytoarchitectonically distinct areas in the
                      posterior insula. The examined brains were then 3D
                      reconstructed and spatially normalized to the Montreal
                      Neurological Institute single-subject template.
                      Probabilistic maps for each area were calculated by
                      superimposing the individual delineations, and a
                      cytoarchitectonic summary map was computed to chart the
                      regional architectonic organization. These maps can be used
                      to identify the anatomical correlates of functional
                      activations observed in neuroimaging studies and to
                      understand the microstructural correlates of the functional
                      segregation of the human posterior insula.},
      keywords     = {Adult / Aged / Aged, 80 and over / Brain Mapping: methods /
                      Cerebral Cortex: cytology / Cerebral Cortex: physiology /
                      Female / Functional Laterality: physiology / Humans /
                      Imaging, Three-Dimensional / Male / Middle Aged / Models,
                      Statistical / Nerve Fibers, Myelinated: physiology / Neural
                      Pathways: anatomy $\&$ histology / Neural Pathways: cytology
                      / Neural Pathways: physiology / Neurons: cytology / Neurons:
                      physiology / J (WoSType)},
      cin          = {INM-2 / INM-1 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-2-20090406 / I:(DE-Juel1)INM-1-20090406 /
                      $I:(DE-82)080010_20140620$},
      pnm          = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
                      89571 - Connectivity and Activity (POF2-89571)},
      pid          = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89571},
      shelfmark    = {Neurosciences},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:19822572},
      pmc          = {pmc:PMC2871375},
      UT           = {WOS:000277985800018},
      doi          = {10.1093/cercor/bhp208},
      url          = {https://juser.fz-juelich.de/record/9710},
}