% IMPORTANT: The following is UTF-8 encoded. This means that in the presence % of non-ASCII characters, it will not work with BibTeX 0.99 or older. % Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or % “biber”. @ARTICLE{RezaeiGhaleh:996126, author = {Rezaei-Ghaleh, Nasrollah and Agudo-Canalejo, Jaime and Griesinger, Christian and Golestanian, Ramin}, title = {{R}esponse to {C}omment on “{F}ollowing {M}olecular {M}obility during {C}hemical {R}eactions: {N}o {E}vidence for {A}ctive {P}ropulsion” and “{M}olecular {D}iffusivity of {C}lick {R}eaction {C}omponents: {T}he {D}iffusion {E}nhancement {Q}uestion”}, journal = {Journal of the American Chemical Society}, volume = {144}, number = {30}, issn = {0002-7863}, address = {Washington, DC}, publisher = {ACS Publications}, reportid = {FZJ-2023-01123}, pages = {13441 - 13445}, year = {2022}, abstract = {In their Comment (DOI: 10.1021/jacs.2c02965) on two related publications by our group (J. Am. Chem. Soc. 2022,144, 1380−1388; DOI: 10.1021/jacs.1c11754) and another (J. Am. Chem. Soc. 2021, 143, 20884−20890; DOI: 10.1021/jacs.1c09455), Huang and Granick refer to the diffusion NMR measurements of molecules during a copper-catalyzed azide−alkyne cycloaddition (CuAAC) “click” reaction. Here we respond to their comments and maintain that no measurable diffusion enhancement was observed during the reaction. We expand on the physical arguments presented in our original JACS Article regarding the appropriate reference state for the diffusion coefficient and present new data showing that the use of other reference states, as suggested by Huang and Granick, will still support our conclusion that the two reactants and one product of the CuAAC reaction do not exhibit boosted mobility during the reaction.}, cin = {IBI-7}, ddc = {540}, cid = {I:(DE-Juel1)IBI-7-20200312}, pnm = {5241 - Molecular Information Processing in Cellular Systems (POF4-524)}, pid = {G:(DE-HGF)POF4-5241}, typ = {PUB:(DE-HGF)16}, pubmed = {35919985}, UT = {WOS:000835696600001}, doi = {10.1021/jacs.2c02850}, url = {https://juser.fz-juelich.de/record/996126}, }