Vita Publikationen

This study presents a comparison of numerical and experimental results of the steady flow field in the left main-bronchus of the upper human airways during exhalation. Stereo-particle-image velocimetry measurements were performed in multiple parallel measurement planes for a Reynolds number of Re_D = 700 based on the hydraulic diameter of the trachea to determine the highly three-dimensional flow in a realistic transparent silicone lung model. [...]

Computational fluid dynamics methods enable to numerically predict complex flows with the help of computers. In the fields of Engineering and Physics they are already in use for decades to support design decissions and to get insight into complex physical phenomena. [...]

The report reflects an agreement based on the consensus conference of the International Standardization Committee on the Objective Assessment of the Nasal Airway in Riga, 2nd Nov. 2016. [...]

In this study nasal allergen challenge tests have been performed with high resolution MR-imaging of the head, as a basis for 3D-visualization of the spatial distribution of mucosal swelling in the nasal cavity. The purpose of this investigation was to document the protective effect of Mometasone furoate nasal spray (MFNS) on exposure to allergens..

In this diploma thesis, the accuracy of three-dimensional surface reconstructions of the human nasal cavity from Computer Tomography (CT) volume images is analyzed. For this purpose, a reconstruction pipeline is developed, allowing the extraction of the nasal cavity surface, which then can be used to carry out flow simulations to analyze breathing problems. [...]

Complaints like impaired respiration capabilities or a reduced sense of smell and taste are common for pathologically shaped nasal cavities. The Lattice-Boltzmann Method (LBM), which is particularly suited to simulate flows in intricate geometries, is used to analyze the influence of the geometry of the nasal cavity on the pressure loss in a non-invasive pre-surgical step to support surgical decision processes. [...]

This systematic review aims first to summarize the previous areas of application of computational fluid dynamics (CFD) and then to demonstrate that CFD is also a suitable instrument for generating three-dimensional images that depict drug effects on nasal mucosa. Special emphasis is placed on the three-dimensional visualization of the antiobstructive effect of nasal steroids and antihistamines in the treatment of allergic rhinitis. [...]

Abstract Impaired respiration capabilities or a reduced sense of smell and taste are common for pathologically shaped nasal cavities. To analyze the flow in the human nasal cavity, simulations with a Lattice-Boltzmann Method (LBM) are carried out. [...]

To analyze rhinological complaints like a reduction of breathing capa- bilities, performance reduction of the olfactory organ, and complaints inherited by diminished heating and moisturizing functions of the human nasal cavity, flow simulations with a Lattice-Boltzmann method are carried out using refined Cartesian meshes to resolve, e.g., the wall-bounded shear layers. This method is particularly suited for flows in highly intricate geometries. [...]

Within this work the flow in the human nasal cavity is investigated using Computa-tional Fluid Dynamics (CFD) methods. Different approaches exist to numerically sim-ulate flows, e.g., Finite-Volume Methods (FVM), and Finite-Element Methods (FEM). [...]