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Major depression disorder (MDD) is a complex neuropsychiatric disorder and an increasing number of genetic risk variants are being identified. Investigation of their influence in the general population requires accurate and efficient assessment of depressive symptoms. [...]

First reports on the application of deep brain stimulation (DBS) of the Nucleus basalis of Meynert (NBM) showed feasibility and safety of the intervention in patients with Alzheimer´s disease. However, clinical effects vary and the mechanisms of actions are still not well understood. [...]

Using grazing incidence scattering methods allows for depth profiling near surface structures very efficiently Dosch (1986). In parallel, layered structures have been used as resonators to enhance the wave field Kozhevnikov et al. [...]

Recent years have seen substantial progress in studying the structural and functional properties of GABAergic interneurons and their roles in the neuronal networks of barrel cortex. Although GABAergic interneurons represent only about 12% of the total number of neocortical neurons, they are extremely diverse with respect to their structural and functional properties. [...]

The work described demonstrates the ability of chemo-enzymatic and enzymatic cascades to form complex stereocomplementary 1,3,4-trisubstituted tetrahydroisoquinolines (THIQ) with three chiral centres in a step-efficient and selective manner, without requiring the purification of intermediates. The cascade starting from cheap substrates (3-hydroxybenzaldehyde and pyruvate) involves a carboligation step, a subsequent transamination and finally, together with a carbonyl co-substrate, a Pictet-Spengler-reaction. [...]