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To better understand the relationship between connectivity and function in the brain at different scales, in this work we show the results of using point-neuron network simulations to complement connectivity information from whole brain simulations based on a dynamic neuron mass model. In our multiscale approach, we simulate a whole brain parcellated into 68 regions using a setup similar to that described in Deco et al. [...]

Die Methode Three-dimensional Polarized Light Imaging (3D-PLI) wurde am Institut für Neurowissenschaften und Medizin am Forschungszentrum Jülich entwickelt. Damit ist es möglich den Verlauf von Nervenfasern im menschlichen Gehirn am Rechner zu rekonstruieren.Das Gehirn wird bei dieser Methode post mortem in 60 μm dicke Scheiben geschnitten und anschließend mit polarisiertem Licht durchleuchtet. [...]

The geological disposal of nuclear waste is based on the multi-barrier concept, comprising various engineered and natural barriers, to confine the radioactive waste and isolate it from the biosphere. Some of the planned repositories for high-level nuclear waste will be hosted in fractured crystalline rock formations. [...]