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2024-04-19
19:10
DBCoverage [FZJ-2024-03000] Journal Article
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Cryo-EM structures of lipidic fibrils of amyloid-β (1-40)
Alzheimer’s disease (AD) is a progressive and incurable neurodegenerative disease characterized by the extracellular deposition of amyloid plaques. Investigation into the composition of these plaques revealed a high amount of amyloid-β (Aβ) fibrils and a high concentration of lipids, suggesting that fibrillipid interactions may also be relevant for the pathogenesis of AD. [...]

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2024-04-12
11:22

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2024-04-12
09:52

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2024-04-12
09:51
[FZJ-2024-02717] Journal Article
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Magnetic exchange interactions at the proximity of a superconductor
Interfacing magnetism with superconductivity gives rise to a wonderful playground for intertwining key degrees of freedom: Cooper pairs, spin, charge, and spin-orbit interaction, from which emerge a wealth of exciting phenomena, fundamental in the nascent field of superconducting spinorbitronics and topological quantum technologies. Magnetic exchange interactions (MEI), being isotropic or chiral such as the Dzyaloshinskii Moriya interactions (DMI), are vital in establishing the magnetic behavior at these interfaces as well as in dictating not only complex transport phenomena, but also the manifestation of topologically trivial or non-trivial objects as skyrmions, spirals, Yu-Shiba-Rusinov states and Majorana modes. [...]
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2024-04-12
09:49
[FZJ-2024-02715] Journal Article
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Unbalanced penalization: a new approach to encode inequality constraints of combinatorial problems for quantum optimization algorithms
Solving combinatorial optimization problems of the kind that can be codified by quadratic unconstrained binary optimization (QUBO) is a promising application of quantum computation. Some problems of this class suitable for practical applications such as the traveling salesman problem (TSP), the bin packing problem (BPP), or the knapsack problem (KP) have inequality constraints that require a particular cost function encoding. [...]
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2024-04-12
09:36

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2024-04-12
09:22

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2024-04-11
10:51

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2024-04-10
08:35

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2024-04-10
08:19
OpenAccess [FZJ-2024-02535] Journal Article
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The coming decade of digital brain research: A vision for neuroscience at the intersection of technology and computing
In recent years, brain research has indisputably entered a new epoch, driven by substantial methodological advances and digitally enabled data integration and modelling at multiple scales— from molecules to the whole brain. Major advances are emerging at the intersection of neuroscience with technology and computing. [...]
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