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This paper presents a data-driven method to identify possible heating supply temperature reductions in existing buildings, which can improve the efficiency of heat supply systems such as heat pumps or district heating. Traditional analysis for supply temperature reduction is often associated with high efforts, limiting widespread applications. [...]

The homopentameric α7-nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel widely expressed in the human nervous system and susceptible to allosteric modulation. A recent cryo-EM structure (EMD 22983; PDB ID 7KOX) revealed unassigned Coulomb density. [...]