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The PREFER (Polarization REsearch for Fusion Experiments and Reactors) collaboration aimsto address the know-hows in different fields and techniques to the challenging bet on energyproduction by nuclear fusion with polarized fuel. The collaboration involves different institutionsand researchers, sharing skills and peculiar abilities, having then possibilities to span over a varietyof tasks and objectives, which are under the responsibility of the authors of this contribution,leading their groups [...]

Nuclear spin polarization has important applications across various fields, including physics andmedicine. It also offers several advantages, such as cross-section enhancement, in the five-nucleonfusion reactions, namely the D–T and D–$^3$He reactions. [...]

A new theoretical concept of the quantum mechanical processes in spin filter for the separation ofmetastable hydrogen atoms in individual hyperfine substates enables a number of new applications.For example, it is now possible to build a new generation of Lamb-shift polarimeter that canseparate not only 𝛼 but also the 𝛽 substates with $𝑚_𝐽$ = −1/2. This opens up completely newpossibilities for the search of hydrogen atoms in forbidden substates after the bound beta decayof the neutron. [...]