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@ARTICLE{MartinezRoque:1005150,
author = {Martinez Roque, Mateo Alejandro and Franco-Urquijo, Pablo
Alberto and García-Velásquez, Víctor Miguel and
Choukeife, Moujab and Mayer, Günther and Molina, Sergio and
Figueroa Miranda, Gabriela and Mayer, Dirk and
Alvarez-Salas, Luis M},
title = {{DNA} aptamer selection for {SARS}-{C}o{V}-2 spike
glycoprotein detection},
journal = {Analytical biochemistry},
volume = {645},
issn = {0003-2697},
address = {San Diego, Calif.},
publisher = {Elsevier},
reportid = {FZJ-2023-01338},
pages = {114633},
year = {2022},
abstract = {The rapid spread of SARS-CoV-2 infection throughout the
world led to a global public health and economic crisis
triggering an urgent need for the development of low-cost
vaccines, therapies and high-throughput detection assays. In
this work, we used a combination of Ideal-Filter Capillary
Electrophoresis SELEX (IFCE-SELEX), Next Generation
Sequencing (NGS) and binding assays to isolate and validate
single-stranded DNA aptamers that can specifically recognize
the SARS-CoV-2 Spike glycoprotein. Two selected
non-competing DNA aptamers, C7 and C9 were successfully used
as sensitive and specific biological recognition elements
for the development of electrochemical and fluorescent
aptasensors for the SARS-CoV-2 Spike glycoprotein with
detection limits of 0.07 fM and 41.87 nM, respectively.},
cin = {IBI-3},
ddc = {540},
cid = {I:(DE-Juel1)IBI-3-20200312},
pnm = {5241 - Molecular Information Processing in Cellular Systems
(POF4-524)},
pid = {G:(DE-HGF)POF4-5241},
typ = {PUB:(DE-HGF)16},
pubmed = {35247355},
UT = {WOS:000793071600006},
doi = {10.1016/j.ab.2022.114633},
url = {https://juser.fz-juelich.de/record/1005150},
}