% IMPORTANT: The following is UTF-8 encoded. This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.
@ARTICLE{Saberi:1018071,
author = {Saberi, Amin and Paquola, Casey and Wagstyl, Konrad and
Hettwer, Meike D. and Bernhardt, Boris C. and Eickhoff,
Simon B. and Valk, Sofie L.},
title = {{T}he regional variation of laminar thickness in the human
isocortex is related to cortical hierarchy and interregional
connectivity},
journal = {PLoS biology},
volume = {21},
number = {11},
issn = {1544-9173},
address = {Lawrence, KS},
publisher = {PLoS},
reportid = {FZJ-2023-04522},
pages = {e3002365 -},
year = {2023},
abstract = {The human isocortex consists of tangentially organized
layers with unique cytoarchitectural properties. These
layers show spatial variations in thickness and
cytoarchitecture across the neocortex, which is thought to
support function through enabling targeted corticocortical
connections. Here, leveraging maps of the 6 cortical layers
based on 3D human brain histology, we aimed to
quantitatively characterize the systematic covariation of
laminar structure in the cortex and its functional
consequences. After correcting for the effect of cortical
curvature, we identified a spatial pattern of changes in
laminar thickness covariance from lateral frontal to
posterior occipital regions, which differentiated the
dominance of infra- versus supragranular layer thickness.
Corresponding to the laminar regularities of cortical
connections along cortical hierarchy, the
infragranular-dominant pattern of laminar thickness was
associated with higher hierarchical positions of regions,
mapped based on resting-state effective connectivity in
humans and tract-tracing of structural connections in
macaques. Moreover, we show that regions with similar
laminar thickness patterns have a higher likelihood of
structural connections and strength of functional
connections. In sum, here, we characterize the organization
of laminar thickness in the human isocortex and its
association with cortico-cortical connectivity, illustrating
how laminar organization may provide a foundational
principle of cortical function.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)16},
pubmed = {37943873},
UT = {WOS:001109757500005},
doi = {10.1371/journal.pbio.3002365},
url = {https://juser.fz-juelich.de/record/1018071},
}