001019318 001__ 1019318
001019318 005__ 20231213202052.0
001019318 037__ $$aFZJ-2023-05292
001019318 041__ $$aEnglish
001019318 1001_ $$0P:(DE-Juel1)186710$$aEivazi, Faranak$$b0$$eCorresponding author$$ufzj
001019318 1112_ $$aDPG-Frühjahrstagung, Sektion Kondensierte Materie$$cDresden$$d2023-03-26 - 2023-03-31$$gSKM$$wGermany
001019318 245__ $$aBiomarker detection using Frequency Mixing Magnetic Detection Technique
001019318 260__ $$c2023
001019318 3367_ $$033$$2EndNote$$aConference Paper
001019318 3367_ $$2BibTeX$$aINPROCEEDINGS
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001019318 3367_ $$0PUB:(DE-HGF)24$$2PUB:(DE-HGF)$$aPoster$$bposter$$mposter$$s1702453029_3807$$xOther
001019318 520__ $$aThe electrolyte-insulator-semiconductor sensor (EIS) provides a promising technique for the electrical detection of biomarkers by their intrinsic electrical charge. Due to the charge-screening effect, EIS sensors are less sensitive when samples contain multiple charged species. Our study combines the EIS sensor with the frequency mixing magnetic detection (FMMD) technique to improve functionality and produce more reliable results. The principle of the dual-modality technique is to use superparamagnetic nanoparticles (SPNs) as receptor carriers and pull them towards the surface of the EIS with an external magnet. FMMD exposes SPNs to both low-frequency and high-frequency magnetic fields. The magnetic response of SPNs induces a voltage in the detection coil. The hydrodynamic radius of SPNs can be determined by observing a phase shift toward lower frequencies caused by the Brownian relaxation of the particles. The target can be confirmed when both techniques detect it in a sample. As a result of this dual-modality technique, selectivity and sensitivity can be highly improved.
001019318 536__ $$0G:(DE-HGF)POF4-5241$$a5241 - Molecular Information Processing in Cellular Systems (POF4-524)$$cPOF4-524$$fPOF IV$$x0
001019318 536__ $$0G:(GEPRIS)445454801$$aDFG project 445454801 - Kombinierter Feldeffekt-/Magnet-Immunsensor-Chip für den markierungsfreien Nachweise von Biomarkern (FEMIC) (445454801)$$c445454801$$x1
001019318 7001_ $$0P:(DE-Juel1)128697$$aKrause, Hans-Joachim$$b1$$ufzj
001019318 909CO $$ooai:juser.fz-juelich.de:1019318$$pVDB
001019318 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)186710$$aForschungszentrum Jülich$$b0$$kFZJ
001019318 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)128697$$aForschungszentrum Jülich$$b1$$kFZJ
001019318 9131_ $$0G:(DE-HGF)POF4-524$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5241$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vMolecular and Cellular Information Processing$$x0
001019318 9141_ $$y2023
001019318 920__ $$lyes
001019318 9201_ $$0I:(DE-Juel1)IBI-3-20200312$$kIBI-3$$lBioelektronik$$x0
001019318 980__ $$aposter
001019318 980__ $$aVDB
001019318 980__ $$aI:(DE-Juel1)IBI-3-20200312
001019318 980__ $$aUNRESTRICTED