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@PHDTHESIS{Schwanemann:1019834,
author = {Schwanemann, Tobias},
title = {{S}train- and process engineering for polyketides
production with {P}seudomonas taiwanensis {VLB}120 in
two-phase cultivations},
volume = {276},
school = {Univ. Düsseldorf},
type = {Dissertation},
address = {Jülich},
publisher = {Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag},
reportid = {FZJ-2023-05665},
isbn = {978-3-95806-726-4},
series = {Schriften des Forschungszentrums Jülich Reihe
Schlüsseltechnologien / Key Technologies},
pages = {230},
year = {2023},
note = {Dissertation, Univ. Düsseldorf, 2023},
abstract = {Polyketides are a highly diverse group of secondary
metabolites with great potential for lead compounds for
applications in multiple industries. Biotechnological hosts
are frequently used for their heterologous production. For
polyketide synthesis, identical precursors are assembled to
complex compounds with highly different properties while
using the same cellular resources. Consequently, the choice
of polyketide synthase (PKS) determines the final product
and the interchangeable nature of PKS allows the production
of various compounds by minimal modifications of the host
organism. In particular, PKS III represent an interesting
group of catalysts due to their simplicity compared to other
PKS. In this work, an alternative bacterial production host,
Pseudomonas taiwanensis VLB120, was developed for the
production of various polyketide products in two-phase
cultivations for in situ product removal.},
cin = {IBG-1},
cid = {I:(DE-Juel1)IBG-1-20101118},
pnm = {2172 - Utilization of renewable carbon and energy sources
and engineering of ecosystem functions (POF4-217)},
pid = {G:(DE-HGF)POF4-2172},
typ = {PUB:(DE-HGF)3 / PUB:(DE-HGF)11},
urn = {urn:nbn:de:0001-20240124092709594-7519671-4},
doi = {10.34734/FZJ-2023-05665},
url = {https://juser.fz-juelich.de/record/1019834},
}