Hauptseite > Publikationsdatenbank > Strain- and process engineering for polyketides production with Pseudomonas taiwanensis VLB120 in two-phase cultivations > print

001     1019834
005     20240226075524.0
020 _ _ |a 978-3-95806-726-4
024 7 _ |2 datacite_doi
|a 10.34734/FZJ-2023-05665
024 7 _ |2 URN
|a urn:nbn:de:0001-20240124092709594-7519671-4
037 _ _ |a FZJ-2023-05665
100 1 _ |0 P:(DE-Juel1)178720
|a Schwanemann, Tobias
|b 0
|e Corresponding author
|u fzj
245 _ _ |a Strain- and process engineering for polyketides production with Pseudomonas taiwanensis VLB120 in two-phase cultivations
|f 2020-02-01 - 2023-10-26
260 _ _ |a Jülich
|b Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag
|c 2023
300 _ _ |a 230
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|a Thesis
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|s 1704377477_23155
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490 0 _ |a Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies
|v 276
502 _ _ |a Dissertation, Univ. Düsseldorf, 2023
|b Dissertation
|c Univ. Düsseldorf
|d 2023
520 _ _ |a Polyketides are a highly diverse group of secondary metabolites with great potential for lead compounds for applications in multiple industries. Biotechnological hosts are frequently used for their heterologous production. For polyketide synthesis, identical precursors are assembled to complex compounds with highly different properties while using the same cellular resources. Consequently, the choice of polyketide synthase (PKS) determines the final product and the interchangeable nature of PKS allows the production of various compounds by minimal modifications of the host organism. In particular, PKS III represent an interesting group of catalysts due to their simplicity compared to other PKS. In this work, an alternative bacterial production host, Pseudomonas taiwanensis VLB120, was developed for the production of various polyketide products in two-phase cultivations for in situ product removal.
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|a 2172 - Utilization of renewable carbon and energy sources and engineering of ecosystem functions (POF4-217)
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|b Forschungsbereich Erde und Umwelt
|l Erde im Wandel – Unsere Zukunft nachhaltig gestalten
|v Für eine nachhaltige Bio-Ökonomie – von Ressourcen zu Produkten
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