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@ARTICLE{Manos:1020019,
author = {Manos, Thanos and Diaz, Sandra and Fortel, Igor and
Driscoll, Ira and Zhan, Liang and Leow, Alex},
title = {{E}nhanced simulations of whole-brain dynamics using hybrid
resting-state structural connectomes},
journal = {Frontiers in computational neuroscience},
volume = {17},
issn = {1662-5188},
address = {Lausanne},
publisher = {Frontiers Research Foundation},
reportid = {FZJ-2023-05834},
pages = {1295395},
year = {2023},
abstract = {The human brain, composed of billions of neurons and
synaptic connections, is an intricate network coordinating a
sophisticated balance of excitatory and inhibitory
activities between brain regions. The dynamical balance
between excitation and inhibition is vital for adjusting
neural input/output relationships in cortical networks and
regulating the dynamic range of their responses to stimuli.
To infer this balance using connectomics, we recently
introduced a computational framework based on the Ising
model, which was first developed to explain phase
transitions in ferromagnets, and proposed a novel hybrid
resting-state structural connectome (rsSC). Here, we show
that a generative model based on the Kuramoto phase
oscillator can be used to simulate static and dynamic
functional connectomes (FC) with rsSC as the coupling weight
coefficients, such that the simulated FC aligns well with
the observed FC when compared with that simulated
traditional structural connectome.},
cin = {JSC},
ddc = {610},
cid = {I:(DE-Juel1)JSC-20090406},
pnm = {5111 - Domain-Specific Simulation $\&$ Data Life Cycle Labs
(SDLs) and Research Groups (POF4-511) / HBP SGA3 - Human
Brain Project Specific Grant Agreement 3 (945539) / DFG
project 491111487 - Open-Access-Publikationskosten / 2022 -
2024 / Forschungszentrum Jülich (OAPKFZJ) (491111487) /
SLNS - SimLab Neuroscience (Helmholtz-SLNS)},
pid = {G:(DE-HGF)POF4-5111 / G:(EU-Grant)945539 /
G:(GEPRIS)491111487 / G:(DE-Juel1)Helmholtz-SLNS},
typ = {PUB:(DE-HGF)16},
pubmed = {38188355},
UT = {WOS:001134314300001},
doi = {10.3389/fncom.2023.1295395},
url = {https://juser.fz-juelich.de/record/1020019},
}