TY - JOUR
AU - Doering, Elena
AU - Antonopoulos, Georgios
AU - Hönig, Merle C.
AU - van Eimeren, Thilo
AU - Eickhoff, Simon B.
AU - Patil, Kaustubh
AU - Drzezga, Alexander
TI - The Link between Brain age and Alzheimer’s Disease development using different neuroimaging modalities
JO - Alzheimer's and dementia
VL - 19
IS - S3
SN - 1552-5260
CY - Hoboken, NJ
PB - Wiley
M1 - FZJ-2024-02498
SP - e065384
PY - 2023
AB - Brain age (BA) provides a proxy of general brain health through the prediction of chronological age (CA) from neuroimaging data of healthy individuals. During aging, the adult brain undergoes changes both on the morphological and metabolic level. Here, we compare the link between BA predicted from morphology (structural MRI) or metabolism (18F-FDG-PET) and cognitive function, as well as pathophysiological measures of Alzheimer’s disease (AD) in cognitively normal individuals (CN) and patients with mild cognitive impairment (MCI).
LB - PUB:(DE-HGF)16
DO - DOI:10.1002/alz.065384
UR - https://juser.fz-juelich.de/record/1024832
ER -