Home > Publications database > The Link between Brain age and Alzheimer’s Disease development using different neuroimaging modalities |
Journal Article | FZJ-2024-02498 |
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2023
Wiley
Hoboken, NJ
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Please use a persistent id in citations: doi:10.1002/alz.065384 doi:10.34734/FZJ-2024-02498
Abstract: Brain age (BA) provides a proxy of general brain health through the prediction of chronological age (CA) from neuroimaging data of healthy individuals. During aging, the adult brain undergoes changes both on the morphological and metabolic level. Here, we compare the link between BA predicted from morphology (structural MRI) or metabolism (18F-FDG-PET) and cognitive function, as well as pathophysiological measures of Alzheimer’s disease (AD) in cognitively normal individuals (CN) and patients with mild cognitive impairment (MCI).
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