%0 Journal Article %A Lazić, Ivan %A Wirix, Maarten %A Mann, Daniel %A Filopoulou, Aikaterini %A Leidl, Max Leo %A Müller-Caspary, Knut %A Meingast, Arno %A Carlsson, Anna %A de Haas, Felix %A Sachse, Carsten %T Broadening Application Spectrum of iDPC-STEM Imaging from Beam Sensitive Solid Materials to Biological and Cryo Nano-particles Using Single Particle Analysis %J Microscopy and microanalysis %V 29 %N Supplement_1 %@ 1079-8501 %C Oxford %I Oxford University Press %M FZJ-2024-02675 %P 307 - 308 %D 2023 %X In the recent years, scanning transmission electron microscopy (STEM) applying focused electron illumination, has been shown to have the capacity to image extremely electron beam sensitive materials [1, 2], including single molecules trapped within porous Zeolite channels [3, 4]. This has been achieved through integrated differential phase contrast STEM mode, known as iDPC-STEM [5–7], which is a dose efficient imaging technique, with directly interpretable contrast transfer function (CTF) and high signal to noise ratio (SNR), as main advantages over the conventional (S)TEM techniques. Recently, biological nano particle structures at near atomic resolution have been also revealed using iDPC-STEM in combination with single particle analysis (SPA) [8, 9]. Previously, SPA has been almost solely used with conventional TEM (CTEM). %F PUB:(DE-HGF)16 %9 Journal Article %R 10.1093/micmic/ozad067.142 %U https://juser.fz-juelich.de/record/1025087