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001025788 1001_ $$0P:(DE-Juel1)178805$$aGiehl, Kathrin$$b0
001025788 245__ $$aWorking Memory Training Responsiveness in Parkinson’s Disease Is Not Determined by Cortical Thickness or White Matter Lesions
001025788 260__ $$aAmsterdam$$bIOS Press$$c2024
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001025788 520__ $$aPatients with Parkinson's disease are highly vulnerable for cognitive decline. Thus, early intervention by means of working memory training (WMT) may be effective for the preservation of cognition. However, the influence of structural brain properties, i.e., cortical thickness and volume of white matter lesions on training responsiveness have not been studied. Here, behavioral and neuroimaging data of 46 patients with Parkinson's disease, 21 of whom engaged in home-based, computerized adaptive WMT, was analyzed. While cortical thickness and white matter lesions volume were associated with cognitive performance at baseline, these structural brain properties do not seem to determine WMT responsiveness.Keywords: MRI; Parkinson’s disease; Working memory training; cognition; cortical thickness; white matter lesion.
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001025788 7001_ $$0P:(DE-HGF)0$$aTheis, Hendrik$$b1
001025788 7001_ $$0P:(DE-HGF)0$$aOphey, Anja$$b2
001025788 7001_ $$aHammes, Jochen$$b3
001025788 7001_ $$aReker, Paul$$b4
001025788 7001_ $$aEggers, Carsten$$b5
001025788 7001_ $$0P:(DE-Juel1)131720$$aFink, Gereon R.$$b6
001025788 7001_ $$aKalbe, Elke$$b7
001025788 7001_ $$0P:(DE-Juel1)169110$$avan Eimeren, Thilo$$b8$$eCorresponding author
001025788 773__ $$0PERI:(DE-600)2599550-9$$a10.3233/JPD-230367$$gVol. 14, no. 2, p. 347 - 351$$n2$$p347 - 351$$tJournal of Parkinson's Disease$$v14$$x1877-7171$$y2024
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